Literature DB >> 3973971

Antibody response to respiratory syncytial virus structural proteins in children with acute respiratory syncytial virus infection.

R Vainionpää, O Meurman, H Sarkkinen.   

Abstract

The purified respiratory syncytial virus (RSV), Randall strain contained 10 polypeptides (72,000 molecular weight [72K], 66K, 48K, 42K, 40K, 36K, 30K, 23K, 18K, and 15K), 8 of which proved to be virus specific, and polypeptides 48K and 23K were glycosylated. In addition, a high-molecular-weight (150K), virus-specific glycopolypeptide was immunoprecipitated from RSV-infected cell lysate. The antibody response in human sera serially collected from children with primary RSV infection was mainly directed against the polypeptides 30K, 48K, and 72K. The immune response against the other viral proteins was also already detectable in the acute-phase sera. These results indicate that the immune response in RSV infection differs significantly from those for other diseases caused by paramyxoviruses.

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Year:  1985        PMID： 3973971      PMCID： PMC254736     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  23 in total

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Journal:  Virology       Date:  1977-10-15       Impact factor: 3.616

6.  Fluorographic detection of radioactivity in polyacrylamide gels with the water-soluble fluor, sodium salicylate.

Authors:  J P Chamberlain
Journal:  Anal Biochem       Date:  1979-09-15       Impact factor: 3.365

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Authors:  D C Merz; A Scheid; P W Choppin
Journal:  Virology       Date:  1981-02       Impact factor: 3.616

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Journal:  Acta Pathol Microbiol Scand B       Date:  1978-12

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Journal:  J Med Virol       Date:  1984       Impact factor: 2.327

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Authors:  C E Machamer; E C Hayes; S D Gollobin; L K Westfall; H J Zweerink
Journal:  Infect Immun       Date:  1980-03       Impact factor: 3.441
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  9 in total

Review 1.  Immunity to human and bovine respiratory syncytial virus.

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Journal:  Arch Virol       Date:  1990       Impact factor: 2.574

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Authors:  M Waris; T Ziegler; M Kivivirta; O Ruuskanen
Journal:  J Clin Microbiol       Date:  1990-06       Impact factor: 5.948

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Authors:  O Meurman; M Waris; K Hedman
Journal:  J Clin Microbiol       Date:  1992-06       Impact factor: 5.948

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Authors:  W Buraphacheep; W J Britt; W M Sullender
Journal:  J Clin Microbiol       Date:  1997-02       Impact factor: 5.948

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Authors:  C Osiowy; D Horne; R Anderson
Journal:  Clin Diagn Lab Immunol       Date:  1994-11

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Authors:  H Tsutsumi; T Honjo; K Nagai; Y Chiba; S Chiba; S Tsugawa
Journal:  J Clin Microbiol       Date:  1989-09       Impact factor: 5.948

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Journal:  J Clin Microbiol       Date:  1986-06       Impact factor: 5.948

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Authors:  Samadhan J Jadhao; Binh Ha; Courtney McCracken; Tebeb Gebretsadik; Christian Rosas-Salazar; James Chappell; Suman Das; Tina Hartert; Larry J Anderson
Journal:  J Med Virol       Date:  2020-12-29       Impact factor: 20.693

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Authors:  O Ruuskanen; P L Ogra
Journal:  Curr Probl Pediatr       Date:  1993-02
  9 in total

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