Literature DB >> 3973116

Phenytoin hypersensitivity reaction presenting with toxic epidermal necrolysis and severe hepatitis. Report of a patient treated with corticosteroid "pulse therapy".

E F Sherertz, B V Jegasothy, G S Lazarus.   

Abstract

In this report we describe the successful outcome following the use of corticosteroid pulse therapy in a patient with a severe phenytoin hypersensitivity reaction presenting with toxic epidermal necrolysis and severe hepatitis. Steroid pulse therapy may be lifesaving in a severe dermatosis, such as toxic epidermal necrolysis.

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Year:  1985        PMID: 3973116     DOI: 10.1016/s0190-9622(85)80012-8

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  7 in total

1.  Intravenous immunoglobulins for the management of Stevens-Johnson syndrome with minimal skin manifestations.

Authors:  Christos S Zipitis; Nandu Thalange
Journal:  Eur J Pediatr       Date:  2006-09-29       Impact factor: 3.183

Review 2.  Anticonvulsant hypersensitivity syndrome in children: incidence, prevention and management.

Authors:  Alberto Verrotti; Daniela Trotta; Carmela Salladini; Francesco Chiarelli
Journal:  CNS Drugs       Date:  2002       Impact factor: 5.749

Review 3.  Anticonvulsant hypersensitivity syndrome: incidence, prevention and management.

Authors:  S R Knowles; L E Shapiro; N H Shear
Journal:  Drug Saf       Date:  1999-12       Impact factor: 5.606

4.  Anticonvulsant hypersensitivity syndrome. In vitro assessment of risk.

Authors:  N H Shear; S P Spielberg
Journal:  J Clin Invest       Date:  1988-12       Impact factor: 14.808

5.  Toxic epidermal necrolysis and Stevens-Johnson syndrome are induced by soluble Fas ligand.

Authors:  Riichiro Abe; Tadamichi Shimizu; Akihiko Shibaki; Hideki Nakamura; Hirokazu Watanabe; Hiroshi Shimizu
Journal:  Am J Pathol       Date:  2003-05       Impact factor: 4.307

6.  Disease severity and status in Stevens-Johnson syndrome and toxic epidermal necrolysis: Key knowledge gaps and research needs.

Authors:  Rannakoe J Lehloenya
Journal:  Front Med (Lausanne)       Date:  2022-09-12

Review 7.  Current Perspectives on Severe Drug Eruption.

Authors:  Jingzhan Zhang; Zixian Lei; Chen Xu; Juan Zhao; Xiaojing Kang
Journal:  Clin Rev Allergy Immunol       Date:  2021-07-17       Impact factor: 8.667

  7 in total

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