Literature DB >> 3972993

Radioenzymatic assay for trimethoprim in very small serum samples.

R Yogev, C Melick, L Tan-Pong.   

Abstract

A modification of the methotrexate radioassay kit (supplied by New England Enzyme Center) enabled determination of trimethoprim levels in 5-microliter serum samples. An excellent correlation between this assay and high-pressure liquid chromatography assay was found. These preliminary results suggest that with this method rapid determination of trimethoprim levels in very small samples (5 to 10 microliters) can be achieved.

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Year:  1985        PMID: 3972993      PMCID: PMC271624          DOI: 10.1128/jcm.21.2.249-250.1985

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  3 in total

1.  Management of P. carinii pneumonia.

Authors: 
Journal:  N Engl J Med       Date:  1977-01-06       Impact factor: 91.245

2.  Rapid assay for determination of trimethoprim and sulfamethoxazole levels in serum by spectrofluorometry.

Authors:  D M Lichtenwalner; B Suh; B Lorber; A M Sugar
Journal:  Antimicrob Agents Chemother       Date:  1979-11       Impact factor: 5.191

3.  High-performance liquid chromatographic quantitation of trimethoprim, sulfamethoxazole, and N4-acetylsulfamethoxazole in body fluids.

Authors:  A Weber; K E Opheim; G R Siber; J F Ericson; A L Smith
Journal:  J Chromatogr       Date:  1983-12-09
  3 in total

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