Literature DB >> 3972917

Effects of xenon and krypton on regional cerebral blood flow in the rat.

L Junck, V Dhawan, H T Thaler, D A Rottenberg.   

Abstract

The effects of high inspired concentrations of xenon and krypton on regional CBF (rCBF) were assessed in the rat using [14C]iodoantipyrine and quantitative autoradiography. Inhalation of 80% xenon for 1 or 2 min and inhalation of 40% xenon for 2 min were found to have significant effects on rCBF, including average increases of 75-96% in cerebral neocortical regions. Inhalation of 40% xenon for 1 min and of 80% krypton for 2 min had no significant effect on rCBF in most brain regions studied. If xenon inhalation produces effects on rCBF in humans similar to those observed in the rat, such effects could be an important source of error in xenon computed tomography rCBF studies.

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Year:  1985        PMID： 3972917     DOI： 10.1038/jcbfm.1985.16

Source DB:  PubMed          Journal:  J Cereb Blood Flow Metab        ISSN： 0271-678X            Impact factor:   6.200


  6 in total

1.  Xenon-induced flow activation in patients with cerebral insult who undergo xenon-enhanced CT blood flow studies.

Authors:  P Horn; P Vajkoczy; C Thomé; E Muench; L Schilling; P Schmiedek
Journal:  AJNR Am J Neuroradiol       Date:  2001-09       Impact factor: 3.825

2.  Physiologic Effects of Xenon in Xenon-CT Cerebral Blood Flow Studies on Comatose Patients.

Authors:  J A Kosty; W A Kofke; E Maloney-Wilensky; S G Frangos; J M Levine; P D Leroux; E L Zager
Journal:  Transl Stroke Res       Date:  2012-06-15       Impact factor: 6.829

3.  Physiologic implications of adding small amounts of carbon dioxide to the gas mixture during inhalation of xenon.

Authors:  E C Marks; H Yonas; M H Sanders; J T Love; C Maxwell; S Schimmerman
Journal:  Neuroradiology       Date:  1992       Impact factor: 2.804

4.  Neuronal preconditioning by inhalational anesthetics: evidence for the role of plasmalemmal adenosine triphosphate-sensitive potassium channels.

Authors:  Carsten Bantel; Mervyn Maze; Stefan Trapp
Journal:  Anesthesiology       Date:  2009-05       Impact factor: 7.892

5.  Stable-xenon-CT: effects of xenon inhalation on EEG and cardio-respiratory parameters in the human.

Authors:  K Holl; N Nemati; E Kohmura; M R Gaab; M Samii
Journal:  Acta Neurochir (Wien)       Date:  1987       Impact factor: 2.216

6.  Effects of xenon and hypothermia on cerebrovascular pressure reactivity in newborn global hypoxic-ischemic pig model.

Authors:  Elavazhagan Chakkarapani; John Dingley; Kristian Aquilina; Damjan Osredkar; Xun Liu; Marianne Thoresen
Journal:  J Cereb Blood Flow Metab       Date:  2013-07-31       Impact factor: 6.200
  6 in total

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