Literature DB >> 3972670

Peripheral dose to the testes: the design and clinical use of a practical and effective gonadal shield.

B A Fraass, T J Kinsella, F S Harrington, E Glatstein.   

Abstract

A simple and practical gonadal shield has been developed for use near megavoltage radiation fields. The lead shield encloses only the testes, allowing its use with nearly any radiation field that does not include the testes. The dose to the testes with and without the shield has been measured extensively both in phantoms and on patients. The gonadal shield allows a 3 to 10-fold reduction in dose to the testes depending primarily on the distance from the field edge to the gonads. When the shield is used, the gonadal dose is always less than 1% of the patient's prescription dose. Based on our patient studies of testicular injury following conventionally-fractionated irradiation, a dose of less than 50 cGy (1% of a typical 5000 cGy treatment regimen) should preserve normal testicular function.

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Year:  1985        PMID: 3972670     DOI: 10.1016/0360-3016(85)90196-8

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  13 in total

1.  Male reproductive health after childhood, adolescent, and young adult cancers: a report from the Children's Oncology Group.

Authors:  Lisa B Kenney; Laurie E Cohen; Margarett Shnorhavorian; Monika L Metzger; Barbara Lockart; Nobuko Hijiya; Eileen Duffey-Lind; Louis Constine; Daniel Green; Lillian Meacham
Journal:  J Clin Oncol       Date:  2012-05-29       Impact factor: 44.544

Review 2.  Male Fertility Preservation.

Authors:  J Abram McBride; Larry I Lipshultz
Journal:  Curr Urol Rep       Date:  2018-05-17       Impact factor: 3.092

3.  Gonadal shielding technique to preserve fertility in male pediatric patients treated with total body irradiation for stem cell transplantation.

Authors:  M Sayan; R J Cassidy; E E Butker; R H Nanda; L Krishnamurti; M K Khan; N Esiashvili
Journal:  Bone Marrow Transplant       Date:  2016-03-07       Impact factor: 5.483

4.  Adaptive planning using megavoltage fan-beam CT for radiation therapy with testicular shielding.

Authors:  Poonam Yadav; Kevin Kozak; Ranjini Tolakanahalli; V Ramasubramanian; Bhudatt R Paliwal; James S Welsh; Yi Rong
Journal:  Med Dosim       Date:  2011-09-16       Impact factor: 1.482

Review 5.  Fertility preservation strategies for male patients with cancer.

Authors:  Darren J Katz; Thomas F Kolon; Darren R Feldman; John P Mulhall
Journal:  Nat Rev Urol       Date:  2013-07-09       Impact factor: 14.432

Review 6.  Fertility considerations in men with testicular cancer.

Authors:  Neel V Parekh; Scott D Lundy; Sarah C Vij
Journal:  Transl Androl Urol       Date:  2020-01

7.  [The gonadal loading during the irradiation of lymph outflow in operated seminomas. In-vivo dosimetry].

Authors:  G Gruber; N Schwegler
Journal:  Strahlenther Onkol       Date:  1999-04       Impact factor: 3.621

8.  Testicular Dose During Prophylaxis of Heterotopic Ossification with Radiation Therapy.

Authors:  Waleed F Mourad; John K Ma; Satyaseelan Packianathan; Weisi Yan; Sherif G Shaaban; Edward M Marchan; Lamiaa E Abdallah; Rei He; Paul N Mobit; Chunli Claus Yang; Srinivasan Vijayakumar
Journal:  In Vivo       Date:  2017 May-Jun       Impact factor: 2.155

9.  Fertility of male survivors of childhood cancer: a report from the Childhood Cancer Survivor Study.

Authors:  Daniel M Green; Toana Kawashima; Marilyn Stovall; Wendy Leisenring; Charles A Sklar; Ann C Mertens; Sarah S Donaldson; Julianne Byrne; Leslie L Robison
Journal:  J Clin Oncol       Date:  2009-11-30       Impact factor: 44.544

10.  Testicular shield for para-aortic radiotherapy and estimation of gonad doses.

Authors:  R Ravichandran; J P Binukumar; S Kannadhasan; M H Shariff; Kamal El Ghamrawy
Journal:  J Med Phys       Date:  2008-10
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