Literature DB >> 3972074

Ocular instillation of naloxone increases intraocular pressure in morphine-addicted patients: a possible test for detecting misuse of morphine.

F Drago, E Aguglia, A Dal Bello, G B Panissidi, F Bellomio, D Spampinato, G Gorgone.   

Abstract

The effect of conjunctival instillation of naloxone on intraocular pressure has been examined in morphine-addicted patients as compared to non-addicted healthy volunteers. Morphine-addicted subjects showed a lower basal value of intraocular pressure as compared to the control volunteers. The instillation of naloxone caused a normalization of intraocular pressure to a level similar to that of control volunteers. This test seems to be a useful screening method for detecting morphine addiction.

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Year:  1985        PMID： 3972074     DOI： 10.1007/bf02002629

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

1.  The effects of morphine on the release of noradrenaline from the cat isolated nictitating membrane and the guinea-pig ileum myenteric plexus-longitudinal muscle preparation.

Authors:  G Henderson; J Hughes; H W Kosterlitz
Journal:  Br J Pharmacol       Date:  1975-04       Impact factor: 8.739

2.  Effect of intramuscular administration of morphine, atrophine, scopolamine and neostigmine on the human eye.

Authors:  I H LEOPOLD; J H COMROE
Journal:  Arch Ophthal       Date:  1948-09

3.  The local effect of morphine, nalorphine, and codeine on the diameter of the pupil of the eye.

Authors:  N Nomof; H W Elliott; K D Parker
Journal:  Clin Pharmacol Ther       Date:  1968 May-Jun       Impact factor: 6.875

4.  The naloxone conjunctival test in morphine addiction.

Authors:  M Fanciullacci; M Boccuni; U Pietrini; F Sicuteri
Journal:  Eur J Pharmacol       Date:  1980-02-08       Impact factor: 4.432

5.  Effect of morphine on adrenergic transmission in the mouse vas deferens. Assessment of agonist and antogonist potencies of narcotic analgesics.

Authors:  J Hughes; H W Kosterlitz; F M Leslie
Journal:  Br J Pharmacol       Date:  1975-03       Impact factor: 8.739

6.  Opiate receptors in the rabbit iris.

Authors:  F Drago; G Gorgone; F Spina; G Panissidi; A Dal Bello; F Moro; U Scapagnini
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1980       Impact factor: 3.000
  6 in total
  1 in total

1.  Preservation of retina ganglion cell function by morphine in a chronic ocular-hypertensive rat model.

Authors:  Shahid Husain; Yasir Abdul; Craig E Crosson
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-06-28       Impact factor: 4.799
  1 in total

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