Literature DB >> 3970916

Pyruvate prevents the ATP depletion caused by formaldehyde or calcium-chelator esters in the human red cell.

J García-Sancho.   

Abstract

Formaldehyde released during hydrolysis of calcium-chelator esters incorporated into cells blocks glycolysis in the human erythrocyte (Tiffert, T., García-Sancho, J. and Lew, V.L. (1984) Biochim. Biophys. Acta 773, 143-156). This blockade is due to the inhibition of glyceraldehyde-3-phosphate dehydrogenase by NAD+ depletion caused by enzymatic oxidation of formaldehyde coupled to NADH production. The addition of pyruvate to the incubation medium prevents or reverts ATP depletion.

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Year:  1985        PMID： 3970916     DOI： 10.1016/0005-2736(85)90357-8

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  16 in total

1.  Quantitative imaging of human red blood cells infected with Plasmodium falciparum.

Authors:  Alessandro Esposito; Jean-Baptiste Choimet; Jeremy N Skepper; Jakob M A Mauritz; Virgilio L Lew; Clemens F Kaminski; Teresa Tiffert
Journal:  Biophys J       Date:  2010-08-04       Impact factor: 4.033

2.  All or none cell responses of Ca2+-dependent K channels elicited by calcium or lead in human red cells can be explained by heterogeneity of agonist distribution.

Authors:  J Alvarez; J García-Sancho; B Herreros
Journal:  J Membr Biol       Date:  1988-09       Impact factor: 1.843

3.  Effects of deoxygenation on active and passive Ca2+ transport and on the cytoplasmic Ca2+ levels of sickle cell anemia red cells.

Authors:  Z Etzion; T Tiffert; R M Bookchin; V L Lew
Journal:  J Clin Invest       Date:  1993-11       Impact factor: 14.808

4.  Mitochondrial respiratory chain complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug.

Authors:  Joanna I Janowska; Sarah Piel; Nahima Saliba; Claire D Kim; David H Jang; Michael Karlsson; Todd J Kilbaugh; Johannes K Ehinger
Journal:  Toxicol In Vitro       Date:  2020-02-11       Impact factor: 3.500

5.  Evidence for a direct reticulocyte origin of dense red cells in sickle cell anemia.

Authors:  R M Bookchin; O E Ortiz; V L Lew
Journal:  J Clin Invest       Date:  1991-01       Impact factor: 14.808

6.  Effect of 1-chloro-2,4-dinitrobenzene on K+ transport in normal and sickle human red blood cells.

Authors:  M C Muzyamba; J S Gibson
Journal:  J Physiol       Date:  2003-02-07       Impact factor: 5.182

7.  Inhibition of the calcium pump by high cytosolic Ca2+ in intact human red blood cells.

Authors:  A C Pereira; D Samellas; T Tiffert; V L Lew
Journal:  J Physiol       Date:  1993-02       Impact factor: 5.182

8.  Physiological localization of an agonist-sensitive pool of Ca2+ in parotid acinar cells.

Authors:  J K Foskett; P J Gunter-Smith; J E Melvin; R J Turner
Journal:  Proc Natl Acad Sci U S A       Date:  1989-01       Impact factor: 11.205

9.  Evidence against a Role of Elevated Intracellular Ca2+ during Plasmodium falciparum Preinvasion.

Authors:  Viola Introini; Alex Crick; Teresa Tiffert; Jurij Kotar; Yen-Chun Lin; Pietro Cicuta; Virgilio L Lew
Journal:  Biophys J       Date:  2018-04-10       Impact factor: 4.033

10.  Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes.

Authors:  David H Vandorpe; Chang Xu; Boris E Shmukler; Leo E Otterbein; Marie Trudel; Frederick Sachs; Philip A Gottlieb; Carlo Brugnara; Seth L Alper
Journal:  PLoS One       Date:  2010-01-15       Impact factor: 3.240
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