Literature DB >> 3970705

A substrate analog inhibitor for arylsulfatase reduces NK cell cytotoxicity.

D Zucker-Franklin, Z F Nabi.   

Abstract

A synthetic aromatic sulfonate (I), which has been found to be an effective inhibitor of arylsulfatase, reduces NK-cell mediated cytotoxicity by ca. 60% at 10 microM concentration. At lower concentrations the effect is concentration dependent, but no further reduction of cytotoxicity is observed at concentrations above 10 microM.

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Year:  1985        PMID: 3970705     DOI: 10.1016/0006-291x(85)90639-4

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  1 in total

Review 1.  Angiostatic steroids. Method of discovery and mechanism of action.

Authors:  J Folkman; D E Ingber
Journal:  Ann Surg       Date:  1987-09       Impact factor: 12.969

  1 in total

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