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Literature DB >> 3970584

Mitogenic effects of sera from normal and psoriatic subjects on human skin fibroblasts.

Abstract

Sera from normal and psoriatic subjects had similar mitogenic effects when added to monolayer cultures of human skin fibroblasts. Fibroblasts derived from a psoriasis patient proliferated faster in both types of sera than fibroblasts from a normal subject, despite similar rates of proliferation in foetal calf serum. The psoriatic fibroblasts appeared to be inherently capable of a greater response to human serum mitogens than the normal fibroblasts.

Entities: Disease Species

Mesh：

Substances：
Mitogens

Year: 1985 PMID： 3970584 DOI： 10.1007/bf00406474

Source DB: PubMed Journal: Arch Dermatol Res ISSN： 0340-3696 Impact factor: 3.017

5 in total

1. Hyperactivity of fibroblasts cultured from psoriatic skin: I. Faster proliferation and effect of serum withdrawal.

Authors: G C Priestley; L W Adams
Journal: Br J Dermatol Date: 1983-08 Impact factor: 9.302

2. Human skin fibroblasts in culture: procollagen synthesis in the presence of sera from normal human subjects and from patients with dermal fibroses.

Authors: E M Tan; J Uitto; E A Bauer; A Z Eisen
Journal: J Invest Dermatol Date: 1981-06 Impact factor: 8.551

2 in total

Review 1. Psoriatic science.

Authors: C M Rowland Payne
Journal: Br Med J (Clin Res Ed) Date: 1987-11-07

2. Use of Cytokine Mix-, Imiquimod-, and Serum-Induced Monoculture and Lipopolysaccharide- and Interferon Gamma-Treated Co-Culture to Establish In Vitro Psoriasis-like Inflammation Models.

Authors: Katarzyna Bocheńska; Marta Moskot; Magdalena Gabig-Cimińska
Journal: Cells Date: 2021-11-02 Impact factor: 6.600

2 in total

Mitogenic effects of sera from normal and psoriatic subjects on human skin fibroblasts.

1. Hyperactivity of fibroblasts cultured from psoriatic skin: I. Faster proliferation and effect of serum withdrawal.

2. Human skin fibroblasts in culture: procollagen synthesis in the presence of sera from normal human subjects and from patients with dermal fibroses.

3. Hyperactivity of fibroblasts cultured from psoriatic skin: II. Synthesis of macromolecules.

4. Diphenylhydantoin (dilantin) gingival hyperplasia: drug-induced abnormality of connective tissue.

5. Effects of various sera on growth kinetics and collagen synthesis by keloid and normal dermal fibroblasts.

Review 1. Psoriatic science.

2. Use of Cytokine Mix-, Imiquimod-, and Serum-Induced Monoculture and Lipopolysaccharide- and Interferon Gamma-Treated Co-Culture to Establish In Vitro Psoriasis-like Inflammation Models.