Literature DB >> 3969080

Sodium arsenite enhances the cytotoxicity, clastogenicity, and 6-thioguanine-resistant mutagenicity of ultraviolet light in Chinese hamster ovary cells.

T C Lee, R Y Huang, K Y Jan.   

Abstract

Cytotoxicity, chromosome aberrations, and mutations to 6-thioguanine resistance were synergistically increased by incubating the ultraviolet light (UV)-irradiated Chinese hamster ovary (CHO) cells in medium containing sodium arsenite. However, the frequencies of sister-chromatid exchanges and mutations to ouabain resistance induced by UV were not synergistically increased by sodium arsenite. The synergistic effect of sodium arsenite on UV-induced chromosome aberrations varied with cell-harvesting time and decreased with increasing time intervals between UV and sodium arsenite treatments.

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Year:  1985        PMID： 3969080     DOI： 10.1016/0027-5107(85)90210-6

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  21 in total

1.  Combination of bifunctional alkylating agent and arsenic trioxide synergistically suppresses the growth of drug-resistant tumor cells.

Authors:  Pei-Chih Lee; Rajesh Kakadiya; Tsann-Long Su; Te-Chang Lee
Journal:  Neoplasia       Date:  2010-05       Impact factor: 5.715

2.  Suppression of sodium arsenite-potentiated cytotoxicity of ultraviolet light by cycloheximide in Chinese hamster ovary cells.

Authors:  T C Lee; S L Kao; L H Yih
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

3.  Micronucleus frequency in peripheral blood lymphocytes and buccal mucosa cells of copper smelter workers, with special regard to arsenic exposure.

Authors:  D Lewińska; J Palus; M Stepnik; E Dziubałtowska; J Beck; K Rydzyński; A T Natarajan; R Nilsson
Journal:  Int Arch Occup Environ Health       Date:  2007-02-03       Impact factor: 3.015

4.  Effects of arsenic on DNA synthesis in human lymphocytes stimulated by phytohemagglutinin.

Authors:  Z Meng
Journal:  Biol Trace Elem Res       Date:  1993-10       Impact factor: 3.738

5.  Posttreatment with sodium arsenite is coclastogenic in log phase but not in stationary phase.

Authors:  R Y Huang; K Y Jan; T C Lee
Journal:  Hum Genet       Date:  1987-02       Impact factor: 4.132

6.  Effects of arsenic on DNA synthesis in human lymphocytes.

Authors:  Z Meng
Journal:  Arch Environ Contam Toxicol       Date:  1993-11       Impact factor: 2.804

7.  Elevation of glutathione levels and glutathione S-transferase activity in arsenic-resistant Chinese hamster ovary cells.

Authors:  T C Lee; M L Wei; W J Chang; I C Ho; J F Lo; K Y Jan; H Huang
Journal:  In Vitro Cell Dev Biol       Date:  1989-05

8.  Nickel chloride inhibits the DNA repair of UV-treated but not methyl methanesulfonate-treated Chinese hamster ovary cells.

Authors:  S F Lee-Chen; M C Wang; C T Yu; D R Wu; K Y Jan
Journal:  Biol Trace Elem Res       Date:  1993-04       Impact factor: 3.738

Review 9.  Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium.

Authors:  Konstantin Salnikow; Anatoly Zhitkovich
Journal:  Chem Res Toxicol       Date:  2007-10-30       Impact factor: 3.739

10.  Toxicity of sodium arsenite in mouse embryos in vitro and its influence on radiation risk.

Authors:  W U Müller; C Streffer; C Fischer-Lahdo
Journal:  Arch Toxicol       Date:  1986-10       Impact factor: 5.153
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