Literature DB >> 3968200

Effect of refrigerated storage on cefaclor in Mueller-Hinton agar.

A M Surprenant, D A Preston.   

Abstract

Cefaclor is less stable than most cephalosporins in media at 35 degrees C. We demonstrated that the activity of cefaclor in Mueller-Hinton agar diminishes continuously at 4 degrees C, resulting in a loss of two-thirds of the activity within 21 days. We recommend that agar dilution plates for this cephalosporin be prepared on the day of their use.

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Year:  1985        PMID： 3968200      PMCID： PMC271591          DOI： 10.1128/jcm.21.1.133-134.1985

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  6 in total

1.  Hydrolysis of 3-chloro-3-cephems. Intramolecular nucleophilic attack in cefaclor.

Authors:  J M Indelicato; A Dinner; L R Peters; W L Wilham
Journal:  J Med Chem       Date:  1977-07       Impact factor: 7.446

2.  Stability and blood level determinations of cefaclor, a new oral cephalosporin antibiotic.

Authors:  M A Foglesong; J W Lamb; J V Dietz
Journal:  Antimicrob Agents Chemother       Date:  1978-01       Impact factor: 5.191

3.  Summary of laboratory studies on the antibacterial activity of cefaclor.

Authors:  D A Preston
Journal:  Postgrad Med J       Date:  1979       Impact factor: 2.401

4.  Comparative in vitro microbiological activity and stability of cefaclor.

Authors:  A P Gillett; J M Andrews; R Wise
Journal:  Postgrad Med J       Date:  1979       Impact factor: 2.401

5.  Influence of antibiotic stability on the results of in vitro testing procedures.

Authors:  W E Wick
Journal:  J Bacteriol       Date:  1964-05       Impact factor: 3.490

6.  Bioactivity of imipenem as a function of medium, time, and temperature.

Authors:  E J Baron; J A Hindler
Journal:  Antimicrob Agents Chemother       Date:  1984-06       Impact factor: 5.191
  6 in total

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