Literature DB >> 3967762

Differential binding of rabbit fast muscle myosin light chain isoenzymes to regulated actin.

H R Trayer, I P Trayer.   

Abstract

The direct binding of S1(A1) and S1(A2) to regulated actin has been investigated by centrifugation. Binding was measured in the presence of either Mg X AdoPP[NH]P or Mg X ADP at 24 degrees C at various ionic strengths. At low ionic strength, in either the presence or absence of Ca2+, the binding of S1(A1) to regulated actin was always stronger than for S1(A2). As the ionic strength was increased the differential binding between S1(A1) and S1(A2) was still maintained in the presence of Ca2+ but not in its absence. These data are discussed in terms of a modifying role for the N-terminal region of the A1 light chain in regulation of the contractile process.

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Year:  1985        PMID： 3967762     DOI： 10.1016/0014-5793(85)81065-6

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  9 in total

1.  Probing myosin light chain 1 structure with monoclonal antibodies.

Authors:  B Cornillon; A M Cathiard; P Eldin; M Anoal; R Cardinaud; J P Liautard; M Le Cunff; D Mornet; F Pons; J Leger
Journal:  J Muscle Res Cell Motil       Date:  1992-06       Impact factor: 2.698

2.  Steric blocking mechanism explains stretch activation in insect flight muscle.

Authors:  Kenneth C Holmes
Journal:  Proc Natl Acad Sci U S A       Date:  2010-12-21       Impact factor: 11.205

Review 3.  The myosin alkali light chain proteins and their genes.

Authors:  P J Barton; M E Buckingham
Journal:  Biochem J       Date:  1985-10-15       Impact factor: 3.857

Review 4.  Molecular mechanisms of cardiomyopathy phenotypes associated with myosin light chain mutations.

Authors:  Wenrui Huang; Danuta Szczesna-Cordary
Journal:  J Muscle Res Cell Motil       Date:  2015-09-18       Impact factor: 2.698

5.  Unloaded shortening velocity and myosin heavy chain and alkali light chain isoform composition in rat skeletal muscle fibres.

Authors:  R Bottinelli; R Betto; S Schiaffino; C Reggiani
Journal:  J Physiol       Date:  1994-07-15       Impact factor: 5.182

Review 6.  Hereditary heart disease: pathophysiology, clinical presentation, and animal models of HCM, RCM, and DCM associated with mutations in cardiac myosin light chains.

Authors:  Sunil Yadav; Yoel H Sitbon; Katarzyna Kazmierczak; Danuta Szczesna-Cordary
Journal:  Pflugers Arch       Date:  2019-01-31       Impact factor: 3.657

7.  Characterization of a rat myosin alkali light chain gene expressed in ventricular and slow twitch skeletal muscles.

Authors:  M Periasamy; R Wadgaonkar; C Kumar; B J Martin; M A Siddiqui
Journal:  Nucleic Acids Res       Date:  1989-10-11       Impact factor: 16.971

8.  A novel Myosin essential light chain mutation causes hypertrophic cardiomyopathy with late onset and low expressivity.

Authors:  Paal Skytt Andersen; Paula Louise Hedley; Stephen P Page; Petros Syrris; Johanna Catharina Moolman-Smook; William John McKenna; Perry Mark Elliott; Michael Christiansen
Journal:  Biochem Res Int       Date:  2012-04-11

9.  Myofibrillar ATPase activity during isometric contraction and isomyosin composition in rat single skinned muscle fibres.

Authors:  R Bottinelli; M Canepari; C Reggiani; G J Stienen
Journal:  J Physiol       Date:  1994-12-15       Impact factor: 5.182
  9 in total

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