Literature DB >> 3967741

Acute toxicity of folic acid in mice.

M Parchure, R Y Ambaye, V S Lalitha, S V Gokhale.   

Abstract

The toxicity of folic acid (PGA) was studied in different inbred strains of mice. LD50 values of PGA by the i.p. route showed a unique toxicity pattern. In some strains, convulsions, ataxia and weakness were observed. Histopathological study in strains S/RVCri, BDF1, DBA/2 and DBA/2fNCri showed acute renal tubular necrosis.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 3967741     DOI： 10.1007/bf02005881

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  7 in total

Review 1.  Inborn errors of folate metabolism (first of two parts).

Authors:  R E Erbe
Journal:  N Engl J Med       Date:  1975-10-09       Impact factor: 91.245

2.  A new factor in the production and cure of macrocytic anaemias and its relation to other haemopoietic principles curative in pernicious anaemia.

Authors:  L Wills; P W Clutterbuck; B D Evans
Journal:  Biochem J       Date:  1937-11       Impact factor: 3.857

3.  The influence of pregnancy on the acute toxicity of various compounds in mice.

Authors:  R P Beliles
Journal:  Toxicol Appl Pharmacol       Date:  1972-12       Impact factor: 4.219

4.  Neurotoxic action of methyltetrahydrofolate in rat cerebellum unrelated to direct activation of kainate receptors.

Authors:  P J Roberts; G A Foster; E M Thomas
Journal:  Nature       Date:  1981-10-22       Impact factor: 49.962

5.  Kainate-like neurotoxicity of folates.

Authors:  J W Olney; T A Fuller; T de Gubareff
Journal:  Nature       Date:  1981-07-09       Impact factor: 49.962

6.  Current results of the screening program at the Division of Cancer Treatment, National Cancer Institute.

Authors:  A Goldin; J M Venditti; J S Macdonald; F M Muggia; J E Henney; V T Devita
Journal:  Eur J Cancer       Date:  1981-02       Impact factor: 9.162

7.  Genetic marker patterns of inbred strains of mice at the Cancer Research Institute, Bombay.

Authors:  H P Randelia; J Hilgers; J Hilkens; V Kroezen; R Holmes; J Vandeberg
Journal:  Lab Anim       Date:  1983-10       Impact factor: 2.471
  7 in total
  3 in total

1.  Urinary excretion of liver type fatty acid binding protein accurately reflects the degree of tubulointerstitial damage.

Authors:  Takeshi Yokoyama; Atsuko Kamijo-Ikemori; Takeshi Sugaya; Seiko Hoshino; Takashi Yasuda; Kenjiro Kimura
Journal:  Am J Pathol       Date:  2009-05-12       Impact factor: 4.307

2.  MRI of tumor-associated macrophages with clinically applicable iron oxide nanoparticles.

Authors:  Heike E Daldrup-Link; Daniel Golovko; Brian Ruffell; David G Denardo; Rosalinda Castaneda; Celina Ansari; Jianghong Rao; Grigory A Tikhomirov; Michael F Wendland; Claire Corot; Lisa M Coussens
Journal:  Clin Cancer Res       Date:  2011-07-26       Impact factor: 12.531

3.  Adipose Tissue-Derived Stem Cells Reduce Acute and Chronic Kidney Damage in Mice.

Authors:  Marina Burgos-Silva; Patricia Semedo-Kuriki; Cassiano Donizetti-Oliveira; Priscilla Barbosa Costa; Marco Antonio Cenedeze; Meire Ioshie Hiyane; Alvaro Pacheco-Silva; Niels Olsen Saraiva Câmara
Journal:  PLoS One       Date:  2015-11-13       Impact factor: 3.240
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.