Literature DB >> 3967221

Preleukemia and leukemia with 12p- and 19q+ chromosome alterations following Alkeran therapy.

D Wilmoth, M Feder, J Finan, P Nowell.   

Abstract

Among 20 patients with acute nonlymphocytic leukemia or dysmyelopoietic preleukemia secondary to Alkeran therapy for another tumor, four had a del(12)(p11-p12) and four had a translocation to 19q13 among multiple karyotypic alterations in their neoplastic hematopoetic clones. It is suggested that these two cytogenetic abnormalities may occur nonrandomly in such hemic disorders and may play a limited role in their pathogenesis.

Entities:  

Mesh:

Substances:

Year:  1985        PMID: 3967221     DOI: 10.1016/0165-4608(85)90135-9

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN: 0165-4608


  3 in total

1.  The gene encoding the T-cell surface protein T4 is located on human chromosome 12.

Authors:  M Isobe; K Huebner; P J Maddon; D R Littman; R Axel; C M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

2.  The human VAV proto-oncogene maps to chromosome region 19p12----19p13.2.

Authors:  C Martinerie; L A Cannizzaro; C M Croce; K Huebner; S Katzav; M Barbacid
Journal:  Hum Genet       Date:  1990-11       Impact factor: 4.132

3.  Confirmation and refinement of the localisation of the c-MEL locus on chromosome 19 by physical and genetic mapping.

Authors:  E Nimmo; R A Padua; D Hughes; J D Brook; R Williamson; K J Johnson
Journal:  Hum Genet       Date:  1989-03       Impact factor: 4.132

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.