| Literature DB >> 396664 |
K Juul, P Sørensen, J Pedersen-Bjergaard, M K Jensen.
Abstract
18 patients with acute non-lymphocytic leukaemia were treated with Prednimustine, a chlorambucil ester of prednisolone, as a single drug. 5 patients responded with falling blast counts in peripheral blood, but only 1 obtained a complete remission of 3 months' duration. Since the activity of Prednimustine is lower than that of other commonly used drugs in acute non-lymphocytic leukaemia, future studies should concentrate on other aspects, such as treatment of patients with steroid receptor-positive blast cells or other types of leukaemia.Entities:
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Year: 1979 PMID: 396664 DOI: 10.1111/j.1600-0609.1979.tb02738.x
Source DB: PubMed Journal: Scand J Haematol ISSN: 0036-553X