Literature DB >> 3964340

HDL2 and HDL3 lipid levels in coronary artery disease.

L Wallentin, B Sundin.   

Abstract

The concentrations of cholesterol (C) and phospholipid (PL) levels in the high density lipoprotein (HDL) fraction and the HDL2 and HDL3 subfractions were determined in 74 men with incapacitating angina pectoris and coronary artery disease (CAD) verified by angiography. An equal number of randomly sampled healthy men matched for age, occupation and place of living constituted the control group. The HDL2 and HDL3 fractions were separated by a combination of ultracentrifugation and precipitation. The levels of HDL-C and HDL-PL were reduced in the CAD patients. The reduction of HDL lipids was attributed to both the HDL2 and HDL3 fractions. Proportionally there was a greater reduction of C and PL in HDL2 than in HDL3. The decrease of HDL2-C and HDL3-PL were significant also after allowance for the influences of obesity and triglyceride level. The reductions of HDL2 and HDL3 were significant as well in smoking as in nonsmoking CAD patients and both in patients with and without beta-adrenoceptor blocking drugs.

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Year:  1986        PMID： 3964340     DOI： 10.1016/0021-9150(86)90041-9

Source DB:  PubMed          Journal:  Atherosclerosis        ISSN： 0021-9150            Impact factor:   5.162


  5 in total

1.  [Age related decrease of high density lipoproteins (HDL) in women after menopause. Quantification of HDL with genetically determined HDL arylesterase in women with healthy coronary vessels and in women with angiographically verified coronary heart disease].

Authors:  J M Chemnitius; H Winkel; I Meyer; K Schirrmacher; V W Armstrong; H Kreuzer; R Zech
Journal:  Med Klin (Munich)       Date:  1998-03-15

2.  Associations of alcohol consumption with plasma high density lipoprotein cholesterol and its major subfractions: the Caerphilly and Speedwell Collaborative Heart Disease Studies.

Authors:  N E Miller; C H Bolton; T M Hayes; D Bainton; J W Yarnell; I A Baker; P M Sweetnam
Journal:  J Epidemiol Community Health       Date:  1988-09       Impact factor: 3.710

3.  Omega-3 Ethyl Ester Concentrate Decreases Total Apolipoprotein CIII and Increases Antithrombin III in Postmyocardial Infarction Patients.

Authors:  E Swahn; H von Schenck; A G Olsson
Journal:  Clin Drug Investig       Date:  1998       Impact factor: 2.859

4.  High-density lipoprotein enhancement of anticoagulant activities of plasma protein S and activated protein C.

Authors:  J H Griffin; K Kojima; C L Banka; L K Curtiss; J A Fernández
Journal:  J Clin Invest       Date:  1999-01       Impact factor: 14.808

5.  Increased production rates of LDL are common in individuals with low plasma levels of HDL cholesterol, independent of plasma triglyceride concentrations.

Authors:  H N Ginsberg; C Ngai; X J Wang; R Ramakrishnan
Journal:  Arterioscler Thromb       Date:  1993-06
  5 in total

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