Literature DB >> 3962767

Isolation and characterization of lipocortin (lipomodulin).

F Hirata, Y Notsu, R Yamada, Y Ishihara, Y Wano, I Kunos, G Kunos.   

Abstract

Lipocortin is a phospholipase inhibitory protein whose synthesis is induced in various cells by glucocorticoids. At least three species with molecular weights of 40,000, 30,000, and 15,000 are presently known. This protein mimics the anti-inflammatory action of glucocorticoids in vitro as well as in vivo. The synthesis of the protein appears to be associated with the MHC genes.

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Year:  1986        PMID: 3962767     DOI: 10.1007/bf01982617

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  18 in total

1.  The role of glucocorticoid receptor and gene expression in the anti-inflammatory action of dexamethasone.

Authors:  S Tsurufuji; K Sugio; F Takemasa
Journal:  Nature       Date:  1979-08-02       Impact factor: 49.962

Review 2.  Mechanism of action of glucocorticoids.

Authors:  E B Thompson; M E Lippman
Journal:  Metabolism       Date:  1974-02       Impact factor: 8.694

3.  Role of lipomodulin, a phospholipase inhibitory protein, in immunoregulation by thymocytes.

Authors:  F Hirata; M Iwata
Journal:  J Immunol       Date:  1983-04       Impact factor: 5.422

4.  Inhibition of human natural killer (NK) activity and antibody dependent cellular cytotoxicity (ADCC) by lipomodulin, a phospholipase inhibitory protein.

Authors:  T Hattori; F Hirata; T Hoffman; A Hizuta; R B Herberman
Journal:  J Immunol       Date:  1983-08       Impact factor: 5.422

5.  Primary cortisol resistance: a family study.

Authors:  G P Chrousos; A C Vingerhoeds; D L Loriaux; M B Lipsett
Journal:  J Clin Endocrinol Metab       Date:  1983-06       Impact factor: 5.958

6.  Identification of several species of phospholipase inhibitory protein(s) by radioimmunoassay for lipomodulin.

Authors:  F Hirata; Y Notsu; M Iwata; L Parente; M DiRosa; R J Flower
Journal:  Biochem Biophys Res Commun       Date:  1982-11-16       Impact factor: 3.575

7.  Presence of autoantibody for phospholipase inhibitory protein, lipomodulin, in patients with rheumatic diseases.

Authors:  F Hirata; R del Carmine; C A Nelson; J Axelrod; E Schiffmann; A Warabi; A L De Blas; M Nirenberg; V Manganiello; M Vaughan; S Kumagai; I Green; J L Decker; A D Steinberg
Journal:  Proc Natl Acad Sci U S A       Date:  1981-05       Impact factor: 11.205

8.  Glucocorticoid inhibition of zymosan-induced arachidonic acid release by rat alveolar macrophages.

Authors:  M Peters-Golden; J Bathon; R Flores; F Hirata; D S Newcombe
Journal:  Am Rev Respir Dis       Date:  1984-11

9.  Adrenergic receptors: possible mechanism of inverse regulation of alpha- and beta-receptors.

Authors:  G Kunos; I Kunos; F Hirata; E J Ishac
Journal:  J Allergy Clin Immunol       Date:  1985-08       Impact factor: 10.793

10.  The regulation of lipomodulin, a phospholipase inhibitory protein, in rabbit neutrophils by phosphorylation.

Authors:  F Hirata
Journal:  J Biol Chem       Date:  1981-08-10       Impact factor: 5.157

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  9 in total

Review 1.  Ten years research on inflammation revisited.

Authors:  K Brune
Journal:  Agents Actions       Date:  1989-01

Review 2.  Pharmacological implications for neuroreceptor imaging.

Authors:  N P Verhoeff
Journal:  Eur J Nucl Med       Date:  1991

Review 3.  Corticosteroids: do they damage the cardiovascular system?

Authors:  S R Maxwell; R J Moots; M J Kendall
Journal:  Postgrad Med J       Date:  1994-12       Impact factor: 2.401

4.  Leukotrienes are involved in leukocyte recruitment induced by live Histoplasma capsulatum or by the beta-glucan present in their cell wall.

Authors:  A I Medeiros; C L Silva; A Malheiro; C M Maffei; L H Faccioli
Journal:  Br J Pharmacol       Date:  1999-12       Impact factor: 8.739

5.  Circadian rhythm of interleukin-1 production of monocytes and the influence of endogenous and exogenous glucocorticoids in man.

Authors:  P Zabel; H J Horst; C Kreiker; M Schlaak
Journal:  Klin Wochenschr       Date:  1990-12-17

6.  Calcium dependency of prostaglandin E2 production in rat glomerular mesangial cells. Evidence that protein kinase C modulates the Ca2+-dependent activation of phospholipase A2.

Authors:  J V Bonventre; M Swidler
Journal:  J Clin Invest       Date:  1988-07       Impact factor: 14.808

7.  Chemotactic peptide-induced arachidonic acid mobilization in human polymorphonuclear leukocytes.

Authors:  G M Galbraith
Journal:  Am J Pathol       Date:  1988-11       Impact factor: 4.307

8.  Lipocortin-independent effect of dexamethasone on phospholipase activity in a thymic epithelial cell line.

Authors:  A Piltch; L Sun; R A Fava; J Hayashi
Journal:  Biochem J       Date:  1989-07-15       Impact factor: 3.857

Review 9.  Calcium in renal cells. Modulation of calcium-dependent activation of phospholipase A2.

Authors:  J V Bonventre
Journal:  Environ Health Perspect       Date:  1990-03       Impact factor: 9.031

  9 in total

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