Literature DB >> 3962646

Pneumococcal antibodies of different immunoglobulin subclasses in normal and IgG subclass deficient individuals of various ages.

B Rynnel-Dagöö, A Freijd, L Hammarström, V Oxelius, M A Persson, C I Smith.   

Abstract

The distribution of pneumococcal antibody activity of the IgG and IgA subclasses was determined in healthy individuals of various ages using monoclonal antibodies in an enzyme linked immunosorbent assay (ELISA). High IgG 2 antibody activity was found in cord blood and in serum from adults. IgG 1 activity was most pronounced in serum from young children and virtually lacking in serum from adults. Anti-pneumococcal antibodies were found to be low in IgG 2 deficient donors and normal in IgG 3 deficient donors. A maturation from relatively low IgG 1 and IgG 2 antipneumococcal activity in young children to high IgG 2 levels in adults was found in healthy individuals. IgA subclass antipneumococcal activity was correlated to age. Evaluation of the distribution of pneumococcal antibody activity of various subclasses offers a new possibility for studying the immune response to infection and immunization.

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Year:  1986        PMID： 3962646     DOI： 10.3109/00016488609108617

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN： 0001-6489            Impact factor:   1.494


  7 in total

1.  Induction of anti-pneumococcal cell wall polysaccharide antibodies by type 4 pneumococcal polysaccharide-protein conjugates.

Authors:  C Peeters; A M Tenbergen-Meekes; J Poolmann; B Zegers; G Rijkers
Journal:  Med Microbiol Immunol       Date:  1992       Impact factor: 3.402

Review 2.  Immunogenicity and immunochemistry of Streptococcus pneumoniae capsular polysaccharides.

Authors:  J E van Dam; A Fleer; H Snippe
Journal:  Antonie Van Leeuwenhoek       Date:  1990-06       Impact factor: 2.271

3.  Clinical and immunological evaluation of patients with mild IgG1 deficiency.

Authors:  D A Van Kessel; P E Horikx; A J Van Houte; C S De Graaff; H Van Velzen-Blad; G T Rijkers
Journal:  Clin Exp Immunol       Date:  1999-10       Impact factor: 4.330

4.  Serum immunoglobulin G antibody subclass response to respiratory syncytial virus F and G glycoproteins after first, second, and third infections.

Authors:  D K Wagner; P Muelenaer; F W Henderson; M H Snyder; C B Reimer; E E Walsh; L J Anderson; D L Nelson; B R Murphy
Journal:  J Clin Microbiol       Date:  1989-03       Impact factor: 5.948

5.  Class- and subclass-specific pneumococcal antibody levels and response to immunization after bone marrow transplantation.

Authors:  J E Lortan; A Vellodi; E S Jurges; K Hugh-Jones
Journal:  Clin Exp Immunol       Date:  1992-06       Impact factor: 4.330

6.  Immunoglobulin G subclass responses to mycobacterial lipoarabinomannan in HIV-infected and non-infected patients with tuberculosis.

Authors:  C T Da Costa; S Khanolkar-Young; A M Elliott; K M Wasunna; K P McAdam
Journal:  Clin Exp Immunol       Date:  1993-01       Impact factor: 4.330

7.  Production and characterization of mouse monoclonal antibodies recognizing multiple subclasses of human IgG.

Authors:  Fatemeh Hajighasemi; Fazel Shokri
Journal:  Avicenna J Med Biotechnol       Date:  2010-01
  7 in total

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