Literature DB >> 3962611

Neurotrophic factor for central cholinergic neurones is present in both normal and Alzheimer brain tissue.

C K Atterwill, D M Bowen.   

Abstract

Reaggregate cultures of foetal rat brain grown in a serum-free medium were used to determine the presence or absence of cholinergic neurotrophic factors in Alzheimer's disease brain tissue. These preliminary data show that both normal and Alzheimer's disease brain contain factors which elevate choline acetyltransferase activity in the reaggregate cultures.

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Year:  1986        PMID： 3962611     DOI： 10.1007/bf00688315

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


  10 in total

1.  Evidence for the presence of specific receptors for insulin-like growth factors 1 (IGE-1) and 2 (IGF-2) and insulin throughout the adult human brain.

Authors:  V R Sara; K Hall; H Von Holtz; R Humbel; B Sjögren; L Wetterberg
Journal:  Neurosci Lett       Date:  1982-12-23       Impact factor: 3.046

2.  The output of neuronotrophic and neurite-promoting agents from rat brain astroglial cells: a microculture method for screening potential regulatory molecules.

Authors:  J S Rudge; M Manthorpe; S Varon
Journal:  Brain Res       Date:  1985-04       Impact factor: 3.252

3.  Is Alzheimer disease caused by lack of nerve growth factor?

Authors:  F Hefti
Journal:  Ann Neurol       Date:  1983-01       Impact factor: 10.422

4.  In vitro Evidence for two distinct hippocampal growth factors: basis of neuronal plasticity?

Authors:  K A Crutcher; F Collins
Journal:  Science       Date:  1982-07-02       Impact factor: 47.728

5.  Development of markers for cholinergic neurones in re-aggregate cultures of foetal rat whole brain in serum-containing and serum-free media: effects of triiodothyronine (T3).

Authors:  C K Atterwill; A Kingsbury; J Nicholls; A Prince
Journal:  Br J Pharmacol       Date:  1984-09       Impact factor: 8.739

6.  Triiodothyronine stimulates the production of insulin-like growth factor (IGF) by fetal hypothalamus cells cultured in serum-free medium.

Authors:  M Binoux; A Faivre-Bauman; C Lassarre; A Barret; A Tixier-Vidal
Journal:  Brain Res       Date:  1985-08       Impact factor: 3.252

7.  A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and Alzheimer disease.

Authors:  S H Appel
Journal:  Ann Neurol       Date:  1981-12       Impact factor: 10.422

8.  Neuronotrophic activity for ciliary ganglion neurons. Induction following injury to the brain of neonatal, adult, and aged rats.

Authors:  D L Needels; M Nieto-Sampedro; S R Whittemore; C W Cotman
Journal:  Brain Res       Date:  1985-02       Impact factor: 3.252

9.  Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease.

Authors:  D M Bowen; S J Allen; J S Benton; M J Goodhardt; E A Haan; A M Palmer; N R Sims; C C Smith; J A Spillane; M M Esiri; D Neary; J S Snowdon; G K Wilcock; A N Davison
Journal:  J Neurochem       Date:  1983-07       Impact factor: 5.372

10.  Somatomedins in aging and dementia disorders of the Alzheimer type.

Authors:  V R Sara; K Hall; K Enzell; A Gardner; R Morawski; L Wetterberg
Journal:  Neurobiol Aging       Date:  1982       Impact factor: 4.673
  10 in total
  2 in total

1.  beta-Amyloid precursor protein isoforms show correlations with neurones but not with glia of demented subjects.

Authors:  A W Procter; P T Francis; C Holmes; M T Webster; M Qume; G C Stratmann; R Doshi; D M Mann; P J Harrison; R C Pearson
Journal:  Acta Neuropathol       Date:  1994       Impact factor: 17.088

2.  The formation of prostaglandins in the postmortem cerebral cortex of Alzheimer-type dementia patients.

Authors:  N Iwamoto; K Kobayashi; K Kosaka
Journal:  J Neurol       Date:  1989-02       Impact factor: 4.849
  2 in total

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