Homologies of nucleotide sequences in the 5'-end regions of two developmentally regulated genes of Sarcophaga peregrina.

In the previous paper we demonstrated that the storage protein gene and 25-kDa protein gene are expressed sequentially in the fat body of middle third-instar Sarcophaga peregrina larvae. In this paper, we showed that the expressions of these two genes are regulated at the transcriptional level, and searched for homologous nucleotide sequences in the two genes in the vicinity of their 5'-ends, assuming that these two genes are regulated by a common mechanism. We selected 9 homologous sequences and found that most of them were distributed in two clusters located between positions -400 and +1. We identified an SV40 enhancer core segment-like sequence in the nontranslated region of the first exons of both genes, which might explain the efficient transcriptions of these two genes.