Literature DB >> 3957642

Herpes encephalitis during pregnancy: failure of acyclovir and adenine arabinoside to prevent neonatal herpes.

S A Berger, M Weinberg, T Treves, P Sorkin, E Geller, G Yedwab, A Tomer, M Rabey, D Michaeli.   

Abstract

A gravid woman with herpes Type II encephalitis delivered an infant with herpes neonatorum despite therapy with acyclovir. Acyclovir was not measurable in the baby's serum 10 h after birth. The viral isolate was sensitive to acyclovir in vitro, and the neonatal infection responded to treatment with the drug. Prenatal antiviral therapy may be ineffective in preventing intrauterine herpesvirus infection.

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Year:  1986        PMID: 3957642

Source DB:  PubMed          Journal:  Isr J Med Sci        ISSN: 0021-2180


  5 in total

1.  Successful empiric treatment of HSV hepatitis in pregnancy. Case report and review of the literature.

Authors:  D V Glorioso; P J Molloy; D H Van Thiel; R J Kania
Journal:  Dig Dis Sci       Date:  1996-06       Impact factor: 3.199

2.  Herpes encephalitis and hepatitis in pregnancy: A case report and literature review.

Authors:  Claire M McCarthy; Caroline Conlon; Maria Kennelly; Richard Drew; Stephen Stewart; Michael P Geary
Journal:  Obstet Med       Date:  2020-12-25

Review 3.  Aciclovir. A reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic efficacy.

Authors:  A J Wagstaff; D Faulds; K L Goa
Journal:  Drugs       Date:  1994-01       Impact factor: 9.546

Review 4.  Acyclovir. An updated review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy.

Authors:  J J O'Brien; D M Campoli-Richards
Journal:  Drugs       Date:  1989-03       Impact factor: 9.546

Review 5.  Herpes simplex virus encephalitis in pregnancy - a case report and review of reported patients in the literature.

Authors:  Katherine C Dodd; Benedict D Michael; Besa Ziso; Bode Williams; Ray Borrow; Anita Krishnan; Tom Solomon
Journal:  BMC Res Notes       Date:  2015-04-01
  5 in total

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