Literature DB >> 3954729

The inhibition of parathyroid-hormone actions on gluconeogenesis and phosphate transport by 3-mercaptopicolinate in rabbit renal proximal tubules.

N Yanagawa, O D Jo.   

Abstract

By using a glucose microassay and the technique for isolated renal-tubule perfusion in vitro, the addition of 3-mercaptopicolinate, a gluconeogenesis inhibitor which inhibits phosphoenolpyruvate carboxykinase specifically, was found to abolish the effects of parathyroid hormone on gluconeogenesis and phosphate-transport rate in isolated rabbit renal proximal straight tubules, suggesting that these parathyroid-hormone actions may share some unknown, yet 3-mercaptopicolinate-inhibitable, intracellular processes.

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Year:  1986        PMID: 3954729      PMCID: PMC1153015          DOI: 10.1042/bj2330271

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  16 in total

1.  Ultramicro method for determination of glycogen and glucose by enzymic labeling with adenosine triphosphate-gamma-32P.

Authors:  W L Chick; A A Like
Journal:  Anal Biochem       Date:  1969-11       Impact factor: 3.365

2.  Relationship between rate of gluconeogenesis and content of nicotinamide adenine dinucleotide in renal cortex.

Authors:  S Y Ou; S A Kempson; T P Dousa
Journal:  Life Sci       Date:  1981-09-21       Impact factor: 5.037

3.  Nephron heterogeneity: gluconeogenesis from pyruvate in rabbit nephron.

Authors:  A Maleque; H Endou; C Koseki; F Sakai
Journal:  FEBS Lett       Date:  1980-07-28       Impact factor: 4.124

4.  Cytosolic redox potential and phosphate transport in the proximal tubule of the rabbit. A study in the isolated perfused tubules.

Authors:  N Yanagawa; G T Nagami; K Kurokawa
Journal:  Miner Electrolyte Metab       Date:  1985

5.  Nucleotide inhibition of phosphate transport in the renal proximal tubule.

Authors:  R P Lang; N Yanagawa; E P Nord; L Sakhrani; S H Lee; L G Fine
Journal:  Am J Physiol       Date:  1983-08

6.  3-mercaptopicolinic acid, an inhibitor of gluconeogenesis.

Authors:  N W DiTullio; C E Berkoff; B Blank; V Kostos; E J Stack; H L Saunders
Journal:  Biochem J       Date:  1974-03       Impact factor: 3.857

7.  Dissociation of gluconeogenesis from fluid and phosphate reabsorption in isolated rabbit proximal tubules.

Authors:  N Yanagawa; G T Nagami; O Jo; J Uemasu; K Kurokawa
Journal:  Kidney Int       Date:  1984-06       Impact factor: 10.612

8.  Stimulation of phosphate transport in the proximal tubule by metabolic substrates.

Authors:  S R Gullans; P C Brazy; L J Mandel; V W Dennis
Journal:  Am J Physiol       Date:  1984-10

9.  Nicotinamide adenine dinucleotide and renal response to parathyroid hormone.

Authors:  T J Berndt; F G Knox; S A Kempson; T P Dousa
Journal:  Endocrinology       Date:  1981-05       Impact factor: 4.736

10.  Possible role of nicotinamide adenine dinucleotide as an intracellular regulator of renal transport of phosphate in the rat.

Authors:  S A Kempson; G Colon-Otero; S Y Ou; S T Turner; T P Dousa
Journal:  J Clin Invest       Date:  1981-05       Impact factor: 14.808

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