Literature DB >> 395294

Exoerythrocytic merozoites of Plasmodium berghei in rat hepatic Kupffer cells.

J A Terzakis, J P Vanderberg, D Foley, S Shustak.   

Abstract

Liver biopsies of white rates infected by Plasmodium berghei sporozoites were examined by electron microscopy. Intrahepatocytic schizont development was confirmed. In addition, at 60 and 70 h after sporozoite inoculation, exoerythrocytic merozoites were noted in Kupffer cells of liver sinusoids. Although it is theoretically possible that this observation may be of merozoite development in Kupffer cells, the authors suspect that this example of phagocytosis would be one of the host's natural defenses against sporozoite-transmitted malaria.

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Year:  1979        PMID: 395294     DOI: 10.1111/j.1550-7408.1979.tb04641.x

Source DB:  PubMed          Journal:  J Protozool        ISSN: 0022-3921


  8 in total

Review 1.  The biology of tissue forms and other asexual stages in mammalian plasmodia.

Authors:  J P Verhave; J F Meis
Journal:  Experientia       Date:  1984-12-15

2.  A liver-stage specific antigen of P. berghei identified by a monoclonal antibody.

Authors:  L Winger; A Suhrbier; C A O'Dowd; K J Hodivala; R E Sinden
Journal:  Bull World Health Organ       Date:  1990       Impact factor: 9.408

Review 3.  Imaging Plasmodium immunobiology in the liver, brain, and lung.

Authors:  Ute Frevert; Adéla Nacer; Mynthia Cabrera; Alexandru Movila; Maike Leberl
Journal:  Parasitol Int       Date:  2013-09-27       Impact factor: 2.230

4.  Process development and analysis of liver-stage antigen 1, a preerythrocyte-stage protein-based vaccine for Plasmodium falciparum.

Authors:  Collette J Hillier; Lisa A Ware; Arnoldo Barbosa; Evelina Angov; Jeffrey A Lyon; D Gray Heppner; David E Lanar
Journal:  Infect Immun       Date:  2005-04       Impact factor: 3.441

5.  Exoerythrocytic development of Plasmodium gallinaceum in the White Leghorn chicken.

Authors:  Ute Frevert; Gerald F Späth; Herman Yee
Journal:  Int J Parasitol       Date:  2007-10-12       Impact factor: 3.981

Review 6.  Immunity to liver stage malaria: considerations for vaccine design.

Authors:  Andrew W Taylor-Robinson
Journal:  Immunol Res       Date:  2003       Impact factor: 2.829

7.  Plasmodium falciparum liver stage antigen-1 is cross-linked by tissue transglutaminase.

Authors:  William S Nicoll; John B Sacci; Carlo Rodolfo; Giuseppina Di Giacomo; Mauro Piacentini; Zoe Jm Holland; Christian Doerig; Michael R Hollingdale; David E Lanar
Journal:  Malar J       Date:  2011-01-21       Impact factor: 2.979

8.  Release of hepatic Plasmodium yoelii merozoites into the pulmonary microvasculature.

Authors:  Kerstin Baer; Christian Klotz; Stefan H I Kappe; Thomas Schnieder; Ute Frevert
Journal:  PLoS Pathog       Date:  2007-11       Impact factor: 6.823

  8 in total

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