Iontophoresis of fluorescein into the posterior segment of the rabbit eye.

Iontophoresis of appreciable quantities of fluorescein into the vitreous body of the rabbit results from the use of a high electrical current density over a limited area of the globe. This is achieved by passing current through the fluorescein when it is held against the region of the ora serrata in a tube less than 1 mm in diameter. The retina is destroyed over a corresponding area when the current enters the eye. An electrode is described which is held to the eye by suction and could be practical for clinical applications.