| Literature DB >> 3948147 |
Abstract
The high risk for malignancy for carriers of several congenital chromosomal abnormalities is discussed. We report herein a patient with Klinefelter's syndrome associated with a high grade malignant non-Hodgkin lymphoma. Chromosome analysis of PHA-stimulated lymphocytes showed a mosaic of 46,XXY (90%) and normal 46,XY (10%) metaphases. To our knowledge, this is the third reported case of a malignant non-Hodgkin lymphoma in a patient with Klinefelter's syndrome in the literature.Entities:
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Year: 1986 PMID： 3948147 DOI： 10.1016/0165-4608(86)90008-7
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608