Literature DB >> 3948016

Motoneurone survival activity in extracts of denervated muscle reduced by prior stimulation of the muscle.

M A Hill, M R Bennett.   

Abstract

Inactivation of skeletal muscle by denervation increases motoneurone survival activity in extracts of skeletal muscle. The present investigation shows that electrical stimulation of denervated muscle decreases motoneurone survival activity in extracts of these muscles. The result suggests that motoneurone survival is dependent on a factor(s) in muscle whose synthesis and/or release is regulated by muscle contraction.

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Year:  1986        PMID： 3948016     DOI： 10.1016/0165-3806(86)90201-4

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  3 in total

1.  Levels of mRNA coding for motoneuron growth-promoting factors are increased in denervated muscle.

Authors:  F A Rassendren; E Bloch-Gallego; H Tanaka; C E Henderson
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-01       Impact factor: 11.205

2.  Neurocrescin is specifically cleaved after the sequence DESD in a caspase-3-independent manner.

Authors:  Rina Nagai; Atsuko Uyeda; Takashi Kawasaki; Takahisa Taguchi
Journal:  Cell Mol Neurobiol       Date:  2004-12       Impact factor: 5.046

3.  Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve.

Authors:  H Funakoshi; J Frisén; G Barbany; T Timmusk; O Zachrisson; V M Verge; H Persson
Journal:  J Cell Biol       Date:  1993-10       Impact factor: 10.539
  3 in total

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