Literature DB >> 394795

A double-blind crossover trial of baclofen--a new treatment for the unstable bladder syndrome.

M C Taylor, C P Bates.   

Abstract

Forty patients with the unstable bladder syndrome have been treated in a double-blind crossover trial of baclofen 5 mg qds versus placebo. Baclofen significantly improved diurnal and nocturnal frequency of micturition and the severity of incontinence. Considerable improvement was also obtained with placebo.

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Year:  1979        PMID: 394795     DOI: 10.1111/j.1464-410x.1979.tb03588.x

Source DB:  PubMed          Journal:  Br J Urol        ISSN: 0007-1331


  9 in total

Review 1.  CNS involvement in overactive bladder: pathophysiology and opportunities for pharmacological intervention.

Authors:  Karl-Erik Andersson; Rikard Pehrson
Journal:  Drugs       Date:  2003       Impact factor: 9.546

Review 2.  Urinary incontinence in the elderly. Causes and treatment options.

Authors:  S Z Nasr; J G Ouslander
Journal:  Drugs Aging       Date:  1998-05       Impact factor: 3.923

3.  The use of oxybutynin in urological practice.

Authors:  Z Kirkali; R H Whitaker
Journal:  Int Urol Nephrol       Date:  1987       Impact factor: 2.370

4.  Oxybutynin hydrochloride in the management of detrusor instability.

Authors:  G Primus; K Pummer
Journal:  Int Urol Nephrol       Date:  1990       Impact factor: 2.370

Review 5.  Pharmacotherapy for nocturia in the elderly patient.

Authors:  Ragnar Asplund
Journal:  Drugs Aging       Date:  2007       Impact factor: 3.923

6.  Central effects of baclofen on the L-dopa induced hyperactive urinary bladder of the rat.

Authors:  U Sillén; B Persson; A Rubenson
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-09       Impact factor: 3.000

Review 7.  Current concepts in the treatment of disorders of micturition.

Authors:  K E Andersson
Journal:  Drugs       Date:  1988-04       Impact factor: 9.546

8.  ADX71441, a novel, potent and selective positive allosteric modulator of the GABA(B) receptor, shows efficacy in rodent models of overactive bladder.

Authors:  M Kalinichev; S Palea; H Haddouk; I Royer-Urios; V Guilloteau; P Lluel; M Schneider; M Saporito; S Poli
Journal:  Br J Pharmacol       Date:  2014-02       Impact factor: 8.739

9.  Systemic and intrathecal baclofen produce bladder antinociception in rats.

Authors:  Timothy J Ness; Alan Randich; Xin Su; Cary DeWitte; Keith Hildebrand
Journal:  BMC Urol       Date:  2021-10-04       Impact factor: 2.264

  9 in total

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