| Literature DB >> 3947248 |
Abstract
The relative efficacy of trihexiphenidyl hydrochloride, amantadine hydrochloride, and low-dose carbidopa-levodopa in reducing parkinsonian tremor was investigated using objective techniques. Trihexiphenidyl and carbidopa-levodopa decreased tremor by greater than 50%. Some patients responded to one drug but not to the other. Amantadine decreased tremor less than 25%. Monotherapy with trihexiphenidyl or carbidopa-levodopa should be the initial treatment for the tremor of Parkinson's disease.Entities:
Mesh:
Substances:
Year: 1986 PMID: 3947248 DOI: 10.1001/archneur.1986.00520020020009
Source DB: PubMed Journal: Arch Neurol ISSN: 0003-9942