| Literature DB >> 394716 |
T K Rao, D R Stoltz, J L Epler.
Abstract
A purified batch of the artificial sweetener saccharin (S-1022) was assayed for mutagenicity and comutagenicity by the Ames Salmonella assay system. Saccharin was not mutagenic and failed to enhance the mutagenic activity induced by a wide variety of known mutagens. These results do not argue against the tumor-promotor-like activity of saccharin but only indicate that the Ames Salmonella assay is not capable of detecting saccharin as a promoter of mutagenesis.Entities:
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Year: 1979 PMID： 394716 DOI： 10.1007/bf00333621
Source DB: PubMed Journal: Arch Toxicol ISSN： 0340-5761 Impact factor: 5.153