Common variable hypogammaglobulinemia in pregnancy: treatment with high-dose immunoglobulin infusions.

Pregnancy outcomes when the mother has common variable hypogammaglobulinemia are poor unless immunoglobulin levels are returned to normal or near-normal range. Intravenous immunoglobulin infusions are the favored mode of therapy. Here, we report the fifth patient so treated. Weekly doses of 200 mg/kg during the third trimester were required. A healthy term baby was delivered and the postpartum course was uncomplicated.