Literature DB >> 3945122

Response of primary hepatic amyloidosis to melphalan and prednisone: a case report and review of the literature.

M A Gertz, R A Kyle.   

Abstract

We report the first case of biopsy-proven primary hepatic amyloidosis in which histologic regression was demonstrated after therapy with melphalan and prednisone. On the basis of the cumulative reported experience regarding the treatment of this rare plasma cell dyscrasia, we recommend a trial of cytotoxic therapy for patients with primary hepatic amyloidosis.

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Year:  1986        PMID: 3945122     DOI: 10.1016/s0025-6196(12)61853-9

Source DB:  PubMed          Journal:  Mayo Clin Proc        ISSN: 0025-6196            Impact factor:   7.616


  4 in total

1.  Antibody-mediated resolution of light chain-associated amyloid deposits.

Authors:  R Hrncic; J Wall; D A Wolfenbarger; C L Murphy; M Schell; D T Weiss; A Solomon
Journal:  Am J Pathol       Date:  2000-10       Impact factor: 4.307

2.  Cholestasis and liver failure with lambda-AL amyloidosis.

Authors:  F Konikoff; C Mor; S Stern; M Shaklai; J Halevy; E Theodor
Journal:  Gut       Date:  1987-07       Impact factor: 23.059

3.  Histological regression of amyloid in AL amyloidosis is exclusively seen after normalization of serum free light chain.

Authors:  Ingrid I van Gameren; Martin H van Rijswijk; Johan Bijzet; Edo Vellenga; Bouke P Hazenberg
Journal:  Haematologica       Date:  2009-08       Impact factor: 9.941

Review 4.  Rapidly progressive obstructive jaundice due to Congo red negative amyloidosis.

Authors:  B M McClements; J H Shanks; C M Hill; C H Cameron; M E Callender
Journal:  Ulster Med J       Date:  1991-10
  4 in total

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