Literature DB >> 3943909

Protection of guinea pigs against cutaneous leishmaniasis by combined infection and chemotherapy.

J El-On, A Witztum, L F Schnur.   

Abstract

A paromomycin and methylbenzethonium chloride ointment cured Leishmania enriettii infections in guinea pigs. Amastigotes were totally eliminated from the treated lesion after 10 days of treatment. A delayed effect also occurred on untreated lesions in the same animals. Lesions treated at various times after infection permitted protective immunity to develop, and 90% of treated animals were refractory to reinfection.

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Year:  1986        PMID: 3943909      PMCID: PMC262416          DOI: 10.1128/iai.51.2.704-706.1986

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  15 in total

1.  The kinetics and quality of acquired resistance in self-healing and metastatic leishmaniasis.

Authors:  L W Poulter
Journal:  Clin Exp Immunol       Date:  1979-04       Impact factor: 4.330

2.  Natural and experimental re-infection of man with Oriental sore.

Authors:  S Y Guirges
Journal:  Ann Trop Med Parasitol       Date:  1971-06

3.  Immunity in cutaneous leishmaniasis of the guinea-pig.

Authors:  A D Bryceson; R S Bray; R A Wolstencroft; D C Dumonde
Journal:  Clin Exp Immunol       Date:  1970-09       Impact factor: 4.330

4.  Problems in leishmaniasis related to immunology.

Authors:  P C Garnham; J H Humphrey
Journal:  Curr Top Microbiol Immunol       Date:  1969       Impact factor: 4.291

5.  Anti-leishmanial activity of immune guinea-pig serum.

Authors:  H Rezai; S Gettner; N Behforouz
Journal:  J Med Microbiol       Date:  1972-08       Impact factor: 2.472

6.  Immunoflorescence studies of Leishmania enriettii infection in the guinea pig.

Authors:  Z K Radwanski; A D Bryceson; P M Preston; D C Dumonde
Journal:  Trans R Soc Trop Med Hyg       Date:  1974       Impact factor: 2.184

Review 7.  Immunological phenomena in leprosy and related diseases.

Authors:  J L Turk; A D Bryceson
Journal:  Adv Immunol       Date:  1971       Impact factor: 3.543

8.  Observations on immunization against cutaneous leishmaniasis in Israel.

Authors:  Z Koufman; N Egoz; C L Greenblatt; E Handman; B Montilio; Z Even-Paz
Journal:  Isr J Med Sci       Date:  1978-02

9.  The quantification of viable Leishmania enriettii from infected guinea-pig tissues.

Authors:  L W Poulter
Journal:  Clin Exp Immunol       Date:  1979-04       Impact factor: 4.330

10.  Antibody-induced movement of membrane components of Leishmania enriettii.

Authors:  J J Doyle; R Behin; J Mauel; D S Rowe
Journal:  J Exp Med       Date:  1974-05-01       Impact factor: 14.307

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  3 in total

1.  The cured immune phenotype achieved by treatment of visceral leishmaniasis in the BALB/c mouse with a nonionic surfactant vesicular formulation of sodium stibogluconate does not protect against reinfection.

Authors:  K C Carter; A J Baillie; A B Mullen
Journal:  Clin Diagn Lab Immunol       Date:  1999-01

2.  Anti-leishmanial effects of trinitroglycerin in BALB/C mice infected with Leishmania major via nitric oxide pathway.

Authors:  Hossein Nahrevanian; Mana Najafzadeh; Reza Hajihosseini; Habib Nazem; Mahin Farahmand; Zahra Zamani
Journal:  Korean J Parasitol       Date:  2009-05-27       Impact factor: 1.341

3.  Inhibition of Murine Systemic Leishmaniasis by Acetyl Salicylic Acid via Nitric Oxide Immunomodulation.

Authors:  H Nahrevanian; M Jalalian; M Farahmand; M Assmar; Ar Esmaeili Rastaghi; M Sayyah
Journal:  Iran J Parasitol       Date:  2012       Impact factor: 1.012

  3 in total

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