Literature DB >> 3943730

Carrier-mediated transport of amino acids through the blood-retinal and the blood-brain barriers.

P Törnquist, A Alm.   

Abstract

The uptake-index method was used to study the transport of amino acids through the blood-retinal and blood-brain barriers in rats. The results indicate the existence of at least two different, similar carriers in both barriers, i.e., one each for neutral and basic amino acids. A third separate transport system for taurine was found in the blood-retinal barrier. All of the carrier systems studied transported amino acids from blood to nervous tissue.

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Year:  1986        PMID： 3943730     DOI： 10.1007/bf02144127

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN： 0721-832X            Impact factor:   3.117


  17 in total

1.  Transport of taurine, L-methionine and 3-o-methyl-D-glucose across frog retinal pigment epithelium.

Authors:  S Miller; R H Steinberg
Journal:  Exp Eye Res       Date:  1976-08       Impact factor: 3.467

2.  Amino acid assignment to one of three blood-brain barrier amino acid carriers.

Authors:  W H Oldendorf; J Szabo
Journal:  Am J Physiol       Date:  1976-01

3.  Distribution of free amino acids and related substances in organs of the rat.

Authors:  J AWAPARA; A J LANDUA; R FUERST
Journal:  Biochim Biophys Acta       Date:  1950-06

4.  Light stimulated release of [35 S]Taurine from chicken retina.

Authors:  H Pasantes-Morales; P F Urban; J Klethi; P Mandel
Journal:  Brain Res       Date:  1973-03-15       Impact factor: 3.252

5.  Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard.

Authors:  W H Oldendorf
Journal:  Brain Res       Date:  1970-12-01       Impact factor: 3.252

6.  Transport of metabolic substrates through the blood-brain barrier.

Authors:  W M Pardridge; W H Oldendorf
Journal:  J Neurochem       Date:  1977-01       Impact factor: 5.372

7.  A comparison of the transport systems which carry L-methionine across the blood-retinal and blood-brain barriers [proceedings].

Authors:  M E Crockett; P M Daniel; O E Pratt
Journal:  J Physiol       Date:  1978-07       Impact factor: 5.182

8.  Blood-vitreous barrier to amino acids.

Authors:  V N Reddy; B Chakrapani; C P Lim
Journal:  Exp Eye Res       Date:  1977-12       Impact factor: 3.467

9.  Capillary permeability in cat choroid, studied with the single injection technique (II).

Authors:  P Törnquist
Journal:  Acta Physiol Scand       Date:  1979-08

10.  Retinal degeneration in cats fed casein. II. Supplementation with methionine, cysteine, or taurine.

Authors:  E L Berson; K C Hayes; A R Rabin; S Y Schmidt; G Watson
Journal:  Invest Ophthalmol       Date:  1976-01
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  19 in total

1.  Effects of taurine on glial cells apoptosis and taurine transporter expression in retina under diabetic conditions.

Authors:  Kaihong Zeng; Hongxia Xu; Mantian Mi; Ka Chen; Jundong Zhu; Long Yi; Ting Zhang; Qianyong Zhang; Xiaoping Yu
Journal:  Neurochem Res       Date:  2010-06-09       Impact factor: 3.996

Review 2.  Retinal vascular image analysis as a potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal microvasculatures.

Authors:  Niall Patton; Tariq Aslam; Thomas Macgillivray; Alison Pattie; Ian J Deary; Baljean Dhillon
Journal:  J Anat       Date:  2005-04       Impact factor: 2.610

Review 3.  Prodrug strategies in ocular drug delivery.

Authors:  Megha Barot; Mahuya Bagui; Mitan R Gokulgandhi; Ashim K Mitra
Journal:  Med Chem       Date:  2012-07       Impact factor: 2.745

Review 4.  Inner blood-retinal barrier transporters: role of retinal drug delivery.

Authors:  Ken-ichi Hosoya; Masanori Tachikawa
Journal:  Pharm Res       Date:  2009-07-01       Impact factor: 4.200

5.  Component characteristics of the vectorial transport system for taurine in isolated bovine retinal pigment epithelium.

Authors:  S Kundaiker; A A Hussain; J Marshall
Journal:  J Physiol       Date:  1996-04-15       Impact factor: 5.182

6.  Quantitative assessment of the permeability of the rat blood-retinal barrier to small water-soluble non-electrolytes.

Authors:  S L Lightman; A G Palestine; S I Rapoport; E Rechthand
Journal:  J Physiol       Date:  1987-08       Impact factor: 5.182

Review 7.  Retinal microvascular network alterations: potential biomarkers of cerebrovascular and neural diseases.

Authors:  Delia Cabrera DeBuc; Gabor Mark Somfai; Akos Koller
Journal:  Am J Physiol Heart Circ Physiol       Date:  2016-12-06       Impact factor: 4.733

8.  Lipophilicity and transporter influence on blood-retinal barrier permeability: a comparison with blood-brain barrier permeability.

Authors:  Ken-ichi Hosoya; Atsushi Yamamoto; Shin-ichi Akanuma; Masanori Tachikawa
Journal:  Pharm Res       Date:  2010-09-22       Impact factor: 4.200

Review 9.  Consequences of variations in genes that affect dopamine in prefrontal cortex.

Authors:  Adele Diamond
Journal:  Cereb Cortex       Date:  2007-09       Impact factor: 5.357

10.  The effect of sodium iodate on the blood-retinal and blood-brain barriers.

Authors:  J Taarnhöj; A Alm
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1992       Impact factor: 3.117
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