Literature DB >> 3942742

Liposome-delivered phosphatidylcholine enhances the acetylcholine sensitivity of dystrophic mouse myotubes.

F Eusebi, G Cossu, M Molinaro, D Giacomoni.   

Abstract

Myotubes were obtained in vitro from satellite cells of normal and dystrophic C57BL/6J/dydy mice. The acetylcholine sensitivity (mV/nC) of dystrophic myotubes determined with conventional electrophysiological techniques, was lower than that of normal myotubes. Incubation of dystrophic myotubes with liposomes containing phosphatidylcholine (a lipid present in higher amounts in normal adult muscle) significantly increased their acetylcholine sensitivity.

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Year:  1986        PMID: 3942742     DOI: 10.1016/0005-2736(86)90206-3

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  1 in total

1.  Physiological characterization of human muscle acetylcholine receptors from ALS patients.

Authors:  Eleonora Palma; Maurizio Inghilleri; Luca Conti; Cristina Deflorio; Vittorio Frasca; Alessia Manteca; Floriana Pichiorri; Cristina Roseti; Gregorio Torchia; Cristina Limatola; Francesca Grassi; Ricardo Miledi
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-29       Impact factor: 11.205

  1 in total

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