Recurrent villous adenoma of the duodenum.

A patient is presented who in 1977 had a villous adenoma of the duodenum presenting with a diarrheal syndrome. Surgical removal of the polypoid mass lesion, which was pathologically a benign villous adenoma, resulted in resolution of her diarrhea. She remained asymptomatic until 6.5 yr later when diarrhea recurred. Radiographic and endoscopic examinations revealed a large villous adenoma within the proximal duodenum. After endoscopic polypectomy, her diarrhea promptly ceased. This is the first reported case of diarrhea associated with a villous adenoma of the duodenum.