Literature DB >> 3940224

Influence of clonogenic assay methodology on measurement of drug sensitivities in vitro.

P J Hepburn, J R Masters.   

Abstract

To assess the influence of clonogenic assay methodology on measurement of reproductive cell kill, the in vitro sensitivities of a human bladder cancer cell line, RT112, to methotrexate and adriamycin were determined using ten different procedures. Marked differences in dose-response to methotrexate, but not adriamycin, were observed.

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Year:  1986        PMID： 3940224     DOI： 10.1007/bf00255293

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN： 0344-5704            Impact factor:   3.333


  3 in total

1.  Timing of assays: an important consideration in the determination of clonogenic cell survival both in vitro and in vivo.

Authors:  P R Twentyman
Journal:  Int J Radiat Oncol Biol Phys       Date:  1979-08       Impact factor: 7.038

2.  The G1 distribution of "G1-less" V79 Chinese hamster cells.

Authors:  R F Brooks; P N Riddle; F N Richmond; J Marsden
Journal:  Exp Cell Res       Date:  1983-10       Impact factor: 3.905

3.  Time-dependent changes in drug sensitivity expressed by mammalian cells after exposure to trypsin.

Authors:  S C Barranco; W E Bolton; J K Novak
Journal:  J Natl Cancer Inst       Date:  1980-04       Impact factor: 13.506
  3 in total

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