| Literature DB >> 3937748 |
R Blomhoff, H K Blomhoff, H Tolleshaug, T B Christensen, T Berg.
Abstract
The plasma half-life of beta-galactosidase in rat was about 1.5 min. Ten minutes after in vivo injection, 45% of the enzyme was recovered in liver, with hepatocytes and endothelial cells as the predominant cell types responsible for uptake. In vitro uptake of beta-galactosidase in hepatocytes and nonparenchymal liver cells was saturable, Ca2+-dependent and it could be partly inhibited by mannose or alpha-methyl-mannoside.Entities:
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Year: 1985 PMID： 3937748 DOI： 10.1016/0020-711x(85)90055-2
Source DB: PubMed Journal: Int J Biochem ISSN： 0020-711X