Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Effects of prednisone and deflazacort on vertebral bone mass.

Literature DB >> 3937579

Effects of prednisone and deflazacort on vertebral bone mass.

Abstract

The effects of a 12-month therapeutic course of two different glucocorticoids, prednisone and deflazacort (an oxazoline derivative of prednisolone), on vertebral and femoral bone was analyzed by dual photon absorptiometry. The data, which reveal a significantly less bone loss with deflazacort (9.7% in 12 months) than with prednisone (21.4% in 12 months), further document the advantage of deflazacort as a glucocorticoid medication in subjects with osteopenic syndromes.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1985 PMID： 3937579 DOI： 10.1007/bf02554912

Source DB: PubMed Journal: Calcif Tissue Int ISSN： 0171-967X Impact factor: 4.333

13 in total

1. Serum 25-hydroxyvitamin D concentrations in patients receiving chronic corticosteroid therapy.

Authors: T J Hahn; L R Halstead; J G Haddad
Journal: J Lab Clin Med Date: 1977-08

2. Corticosteroid osteoporosis.

Authors: J C Gallagher; J Aaron; A Horsman; R Wilkinson; B E Nordin
Journal: Clin Endocrinol Metab Date: 1973-07

3. Mineral loss in cortical and trabecular bone during high-dose prednisone treatment.

Authors: H Rickers; A Deding; C Christiansen; P Rødbro
Journal: Calcif Tissue Int Date: 1984-05 Impact factor: 4.333

4. Bone loss after glucocorticoid therapy.

Authors: V Lo Cascio; E Bonucci; B Imbimbo; P Ballanti; D Tartarotti; G Galvanini; L Fuccella; S Adami
Journal: Calcif Tissue Int Date: 1984-07 Impact factor: 4.333

5. Comparison of subacute effects of oxazacort and prednisone on mineral metabolism in man.

Authors: T J Hahn; L R Halstead; B Strates; B Imbimbo; D T Baran
Journal: Calcif Tissue Int Date: 1980 Impact factor: 4.333

6. Effects of a new glucocorticoid, deflazacort, on pituitary-adrenal function in man: a comparison with prednisone.

Authors: D Criscuolo; F Fraioli; V Bonifacio; D Paolucci; A Isidori
Journal: Int J Clin Pharmacol Ther Toxicol Date: 1980-01

7. Skeletal metabolism and body composition in Cushing's syndrome.

Authors: J F Aloia; M Roginsky; K Ellis; K Shukla; S Cohn
Journal: J Clin Endocrinol Metab Date: 1974-12 Impact factor: 5.958

8. Steroids possessing nitrogen atoms. 3. Synthesis of new highly active corticoids. [17-alpha, 16-alpha-d]oxazolino steroids.

Authors: G Nathanson; G Winters; E Testa
Journal: J Med Chem Date: 1967-09 Impact factor: 7.446

9. Effects of prednisone and deflazacort on mineral metabolism and parathyroid hormone activity in humans.

Authors: C Gennari; B Imbimbo; M Montagnani; M Bernini; P Nardi; L V Avioli
Journal: Calcif Tissue Int Date: 1984-05 Impact factor: 4.333

10. Altered mineral metabolism in glucocorticoid-induced osteopenia. Effect of 25-hydroxyvitamin D administration.

Authors: T J Hahn; L R Halstead; S L Teitelbaum; B H Hahn
Journal: J Clin Invest Date: 1979-08 Impact factor: 14.808

15 in total

1. CGRP receptors mediating CGRP-, adrenomedullin- and amylin-induced relaxation in porcine coronary arteries. Characterization with 'Compound 1' (WO98/11128), a non-peptide antagonist.

Authors: P Hasbak; A Sams; S Schifter; J Longmore; L Edvinsson
Journal: Br J Pharmacol Date: 2001-08 Impact factor: 8.739

2. Comparison of growth retarding effects induced by two different glucocorticoids in prepubertal sick children: an interim long-term analysis.

Authors: G Aicardi; S Milani; B Imbimbo; M Vignolo; E Di Battista; R Gusmano; A Terragna; G Cordone; F Cottafava; R Coppo
Journal: Calcif Tissue Int Date: 1991-04 Impact factor: 4.333

3. Vertebral collapse in juvenile chronic arthritis: its relationship with glucocorticoid therapy.

Authors: S Varonos; B M Ansell; J Reeve
Journal: Calcif Tissue Int Date: 1987-08 Impact factor: 4.333

4. Changes in bone mass during low dose corticosteroid treatment in patients with polymyalgia rheumatica: a double blind, prospective comparison between prednisolone and deflazacort.

Authors: M R Krogsgaard; G Thamsborg; B Lund
Journal: Ann Rheum Dis Date: 1996-02 Impact factor: 19.103

5. Serum osteocalcin (bone Gla-protein) following corticosteroid therapy in postmenopausal women with rheumatoid arthritis. Comparison of the effect of prednisone and deflazacort.

Authors: C Montecucco; F Baldi; A Fortina; G Tomassini; R Caporali; E L Cherie-Ligniere; P Fratino
Journal: Clin Rheumatol Date: 1988-09 Impact factor: 2.980

6. Glucocorticoid-induced osteoporosis in the lumbar spine, forearm, and mandible of nephrotic patients: a double-blind study on the high-dose, long-term effects of prednisone versus deflazacort.

Authors: K Olgaard; T Storm; N van Wowern; H Daugaard; M Egfjord; E Lewin; L Brandi
Journal: Calcif Tissue Int Date: 1992-06 Impact factor: 4.333

10. Comparative study of the effects of different glucocorticosteroids on eosinophil survival primed by cultured epithelial cell supernatants obtained from nasal mucosa and nasal polyps.

Authors: J Mullol; A Xaubet; E López; J Roca-Ferrer; C Picado
Journal: Thorax Date: 1995-03 Impact factor: 9.139