| Literature DB >> 3937430 |
R Brauner, E Thibaud, P Bischof, P C Sizonenko, R Rappaport.
Abstract
The GnRH analogue Buserelin was given for one year to six girls with central precocious puberty in a daily subcutaneous dose of 20 micrograms/kg/day. A decrease of plasma estradiol and vaginal maturation index to prepubertal values was obtained in 5 out of 6 cases. Bone maturation decreased and final predicted adult height improved significantly. This analogue of GnRH appears to be an effective medication for gonadotropin dependent precocious puberty in girls.Entities:
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Year: 1985 PMID: 3937430 DOI: 10.1111/j.1651-2227.1985.tb10062.x
Source DB: PubMed Journal: Acta Paediatr Scand ISSN: 0001-656X