| Literature DB >> 3937115 |
Zsuzsanna Wiesenfeld-Hallin1, Ulf Lindblom.
Abstract
The analgesic properties of systemically administered tocainide, a primary amine congener of lidocaine with a longer duration of action, were examined in rats. Significant antinociception, as assayed on the hot-plate test, was observed after i.p. tocainide at doses below toxic levels. No antinociception was seen with non-toxic doses of lidocaine or bupivacaine.Entities:
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Year: 1985 PMID: 3937115 DOI: 10.1016/0304-3959(85)90005-3
Source DB: PubMed Journal: Pain ISSN: 0304-3959 Impact factor: 6.961