Literature DB >> 3937115

The effect of systemic tocainide, lidocaine and bupivacaine on nociception in the rat.

Zsuzsanna Wiesenfeld-Hallin1, Ulf Lindblom.   

Abstract

The analgesic properties of systemically administered tocainide, a primary amine congener of lidocaine with a longer duration of action, were examined in rats. Significant antinociception, as assayed on the hot-plate test, was observed after i.p. tocainide at doses below toxic levels. No antinociception was seen with non-toxic doses of lidocaine or bupivacaine.

Entities:  

Mesh:

Substances:

Year:  1985        PMID: 3937115     DOI: 10.1016/0304-3959(85)90005-3

Source DB:  PubMed          Journal:  Pain        ISSN: 0304-3959            Impact factor:   6.961


  5 in total

Review 1.  Anaesthesia of farmed fish: implications for welfare.

Authors:  Inger Hilde Zahl; Ole Samuelsen; Anders Kiessling
Journal:  Fish Physiol Biochem       Date:  2011-12-09       Impact factor: 2.794

2.  Antinociceptive effect of ambroxol in rats with neuropathic spinal cord injury pain.

Authors:  Aldric T Hama; Ann Woodhouse Plum; Jacqueline Sagen
Journal:  Pharmacol Biochem Behav       Date:  2010-08-21       Impact factor: 3.533

3.  Systemic tocainide relieves mechanical hypersensitivity and normalizes the responses of hyperexcitable dorsal horn wide-dynamic-range neurons after transient spinal cord ischemia in rats.

Authors:  J X Hao; Y X Yu; A Seiger; Z Wiesenfeld-Hallin
Journal:  Exp Brain Res       Date:  1992       Impact factor: 1.972

Review 4.  The management of central post-stroke pain.

Authors:  D Bowsher
Journal:  Postgrad Med J       Date:  1995-10       Impact factor: 2.401

5.  Antinociception induced by systemic administration of local anaesthetics depends on a central cholinergic mechanism.

Authors:  A Bartolini; A Galli; C Ghelardini; A Giotti; M Malcangio; P Malmberg-Aiello; P L Zucchi
Journal:  Br J Pharmacol       Date:  1987-12       Impact factor: 8.739

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.