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Literature DB >> 393615

A highly sensitive peroxidase-antiperoxidase method for detection of H-Y antigen on cultivated human fibroblasts.

Abstract

A peroxidase-anti-perioxidase method for the detection of H-Y antigen at the single cell level is described. The efficiency of the test was examined in cultivated fibroblasts derived from control subjects and from XX males and a true hermaphrodite. For comparison, H-Y antigen was determined in blood cells of the same probands using the cytotoxic test. The finding of H-Y positive fibroblasts in the intersex patients has implications for the origin of these disorders.

Entities: Disease Species

Mesh：

Substances：
H-Y Antigen

Year: 1979 PMID： 393615 DOI： 10.1007/bf00284609

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

19 in total

1. Appearance of hCG-receptor after conversion of newborn ovarian cells into testicular structures by H-Y antigen in vitro.

Authors: U Müller; M T Zenzes; T Bauknecht; U Wolf; J W Siebers; W Engel
Journal: Hum Genet Date: 1978-12-18 Impact factor: 4.132

2. Demonstration of cell surface antigens and their antibodies by the peroxidase-antiperoxidase method.

Authors: K J Bross; G A Pangalis; C G Staatz; K G Blume
Journal: Transplantation Date: 1978-06 Impact factor: 4.939

3. Simpler technique for serological detection of H-Y antigen on mouse lymphocytes.

Authors: S Tokuda; T Arrington; E H Goldberg; J Richey
Journal: Nature Date: 1977-06-02 Impact factor: 49.962

4. Serological demonstration of H-Y (male) antigen on mouse sperm.

Authors: E H Goldberg; E A Boyse; D Bennett; M Scheid; E A Carswell
Journal: Nature Date: 1971-08-13 Impact factor: 49.962

5. Recessive sex-determining genes in human XX male syndrome.

Authors: A de la Chapelle; G C Koo; S S Wachtel
Journal: Cell Date: 1978-11 Impact factor: 41.582

6. Studies on the function of H-Y antigen: dissociation and reorganization experiments on rat gonadal tissue.

Authors: M T Zenzes; U Wolf; E Günther; W Engel
Journal: Cytogenet Cell Genet Date: 1978

7. Studies on H-Y antigen in different cell fractions of the testis during pubescence: immature germ cells are H-Y antigen negative.

Authors: M T Zenzes; U Müller; I Aschmoneit; U Wolf
Journal: Hum Genet Date: 1978-12-29 Impact factor: 4.132

Review 8. Analytic review: nature and origin of males with XX sex chromosomes.

Authors: A de la Chapelle
Journal: Am J Hum Genet Date: 1972-01 Impact factor: 11.025

9. Serological crossreactivity between H-Y (male) antigens of mouse and man.

Authors: S S Wachtel; G C Koo; E E Zuckerman; U Hammerling; M P Scheid; E A Boyse
Journal: Proc Natl Acad Sci U S A Date: 1974-04 Impact factor: 11.205

10. Association of the H-Y male antigen with beta2-microglobulin on human lymphoid and differentiated mouse teratocarcinoma cell lines.

Authors: M Fellous; E Günther; R Kemler; J Wiels; R Berger; J L Guenet; H Jakob; F Jacob
Journal: J Exp Med Date: 1978-07-01 Impact factor: 14.307

7 in total

A highly sensitive peroxidase-antiperoxidase method for detection of H-Y antigen on cultivated human fibroblasts.

1. Appearance of hCG-receptor after conversion of newborn ovarian cells into testicular structures by H-Y antigen in vitro.

2. Demonstration of cell surface antigens and their antibodies by the peroxidase-antiperoxidase method.

3. Simpler technique for serological detection of H-Y antigen on mouse lymphocytes.

4. Serological demonstration of H-Y (male) antigen on mouse sperm.

5. Recessive sex-determining genes in human XX male syndrome.

6. Studies on the function of H-Y antigen: dissociation and reorganization experiments on rat gonadal tissue.

7. Studies on H-Y antigen in different cell fractions of the testis during pubescence: immature germ cells are H-Y antigen negative.

Review 8. Analytic review: nature and origin of males with XX sex chromosomes.

9. Serological crossreactivity between H-Y (male) antigens of mouse and man.

10. Association of the H-Y male antigen with beta2-microglobulin on human lymphoid and differentiated mouse teratocarcinoma cell lines.

Review 1. Immunological and functional aspects of H-Y antigen.

2. Serology of H-Y antigen.

3. Sex-reversed XY females with campomelic dysplasia are H-Y negative.

4. Comments on the paper by M.T.Zenzes and T.E.Reed: variability in the amount of serologically detectable H-Y antigen.

Review 5. Variability in serologically detected male antigen titer and some resulting problems: a critical review.

6. Identification and function of serologically detectable H-Y antigen.

7. X-linked genes of the H-Y antigen system in the wood lemming (Myopus schisticolor).