Literature DB >> 393525

Characterization of furosemide-induced activation of the renal prostaglandin system.

G Ciabattoni, F Pugliese, G A Cinotti, G Stirati, R Ronci, G Castrucci, A Pierucci, C Patrono.   

Abstract

A detailed time course of changes in plasma renin activity (PRA), urinary prostaglandin (PG) E2, PGF2 alpha, thromboxane (TX) B2 and sodium excretion rates following furosemide was obtained in 7 women. PRA increased within the first 15 min and remained elevated all through the experiment. PGE2, PGF2 alpha, TXB2 and sodium increased simultaneously, reached a peak between 15 and 45 min after furosemide and declined thereafter. It is concluded that furosemide induces a generalized activation of the renal PG system temporally related to the increase of renin release and natriuresis.

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Year:  1979        PMID： 393525     DOI： 10.1016/0014-2999(79)90217-6

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  15 in total

1.  Response to furosemide during dehydration with and without naproxen pretreatment of kidney donors and renal transplant recipients.

Authors:  P A Sjöström; B G Odlind; M Hammarlund-Udenaes
Journal:  Eur J Clin Pharmacol       Date:  1991       Impact factor: 2.953

Review 2.  The involvement of arachidonic acid metabolism in the control of renin release.

Authors:  C Patrono; F Pugliese
Journal:  J Endocrinol Invest       Date:  1980 Apr-Jun       Impact factor: 4.256

3.  The effects of ibuprofen and indomethacin on renal function in the presence and absence of frusemide in healthy volunteers on a restricted sodium diet.

Authors:  A P Passmore; S Copeland; G D Johnston
Journal:  Br J Clin Pharmacol       Date:  1990-03       Impact factor: 4.335

4.  Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects.

Authors:  P Patrignani; P Filabozzi; C Patrono
Journal:  J Clin Invest       Date:  1982-06       Impact factor: 14.808

Review 5.  Interactions of NSAIDs with diuretics and beta-blockers mechanisms and clinical implications.

Authors:  J Webster
Journal:  Drugs       Date:  1985-07       Impact factor: 9.546

6.  Contribution of prostaglandins to the systemic and renal vascular response to frusemide in normal man.

Authors:  I G Mackay; A L Muir; M L Watson
Journal:  Br J Clin Pharmacol       Date:  1984-05       Impact factor: 4.335

7.  Arachidonic acid metabolites, hypertension and arteriosclerosis.

Authors:  P C Weber; W Siess; B Scherer; E Held; H Witzgall; R Lorenz
Journal:  Klin Wochenschr       Date:  1982-05-17

8.  Vascular effects of loop diuretics: an in vivo and in vitro study in the rat.

Authors:  M Barthelmebs; D Stephan; C Fontaine; M Grima; J L Imbs
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1994-02       Impact factor: 3.000

9.  Functional significance of renal prostacyclin and thromboxane A2 production in patients with systemic lupus erythematosus.

Authors:  C Patrono; G Ciabattoni; G Remuzzi; E Gotti; S Bombardieri; O Di Munno; G Tartarelli; G A Cinotti; B M Simonetti; A Pierucci
Journal:  J Clin Invest       Date:  1985-09       Impact factor: 14.808

Review 10.  Prostanoids in paediatric kidney diseases.

Authors:  H W Seyberth; A Leonhardt; B Tönshoff; N Gordjani
Journal:  Pediatr Nephrol       Date:  1991-09       Impact factor: 3.714
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