| Literature DB >> 3934291 |
L Gothefors, C Ahrén, B Stoll, D K Barua, F Orskov, M A Salek, A M Svennerholm.
Abstract
In Dhaka, Bangladesh, fresh isolates of Escherichia coli from 197 patients with diarrhea were investigated for production of enterotoxin and possession of colonization factor antigen (CFA) I or II. Enterotoxigenic E. coli (ETEC) was isolated from 34% of the patients, and of the 67 enterotoxin-positive strains, 75% carried CFAs. Among 68 healthy control persons no strains positive for both enterotoxin and CFA were found. The CFAs in general were restricted to certain serotypes of E. coli. In a subgroup of patients, part of an ongoing surveillance study, mixed infection was seen in 23% of those from whom recognized pathogens were identified. There was a tendency to more severe dehydration when the two virulence factors, enterotoxin and CFA, were simultaneously present.Entities:
Mesh：
Substances：
Year: 1985 PMID： 3934291 DOI： 10.1093/infdis/152.6.1128
Source DB: PubMed Journal: J Infect Dis ISSN： 0022-1899 Impact factor: 5.226