Literature DB >> 393426

In vitro response of chloroquine-resistant Plasmodium falciparum to mefloquine.

F J López Antuñano, W H Wernsdorfer.   

Abstract

The present study was conducted to evaluate the application of the in vitro microtechnique system in determining the response of chloroquine-resistant Plasmodium falciparum to mefloquine.Using isolates of P. falciparum from Boa Vista, Brazil, and Villavicencio, Colombia, mefloquine was more than 7.7, 7.1, 7.1, and 6.4 times more effective than chloroquine in vitro at the ED(90), ED(95), ED(99), and ED(99.9) levels, respectively.

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Year:  1979        PMID: 393426      PMCID: PMC2395824     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN: 0042-9686            Impact factor:   9.408


  3 in total

1.  Chloroquine resistance in Plasmodium falciparum.

Authors:  M D YOUNG; D V MOORE
Journal:  Am J Trop Med Hyg       Date:  1961-05       Impact factor: 2.345

2.  Drug sensitivity of plasmodium falciparum. An in-vitro microtechnique.

Authors:  K H Rieckmann; G H Campbell; L J Sax; J E Mrema
Journal:  Lancet       Date:  1978-01-07       Impact factor: 79.321

3.  Chloroquine resistance of Plasmodium falciparum in Brazil detected by a simple in vitro method.

Authors:  K H Rieckmann; F J López Antuñano
Journal:  Bull World Health Organ       Date:  1971       Impact factor: 9.408

  3 in total
  4 in total

1.  Assessment of chloroquine sensitivity of Plasmodium falciparum in Choluteca, Honduras.

Authors:  P Nguyen-Dinh; J H Hobbs; C C Campbell
Journal:  Bull World Health Organ       Date:  1981       Impact factor: 9.408

2.  Drug-resistant malaria--occurrence, control, and surveillance.

Authors:  W H Wernsdorfer; R L Kouznetsov
Journal:  Bull World Health Organ       Date:  1980       Impact factor: 9.408

3.  Decrease in susceptibility of Plasmodium falciparum to mefloquine in continuous culture.

Authors:  C R Brockelman; S Monkolkeha; P Tanariya
Journal:  Bull World Health Organ       Date:  1981       Impact factor: 9.408

4.  Assessing anti-malarial drug effects ex vivo using the haemozoin detection assay.

Authors:  Maria Rebelo; Carolina Tempera; José F Fernandes; Martin P Grobusch; Thomas Hänscheid
Journal:  Malar J       Date:  2015-04-01       Impact factor: 2.979

  4 in total

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