Literature DB >> 3928828

Valproate-induced hyperammonaemia in two epileptic identical twins.

R Campostrini, G Zaccara, L Rossi, M Paganini, A Dorigotti, R Zappoli.   

Abstract

The cases of two epileptic identical twins are described, one of whom had presented an episode of valproate (VPA)-induced stupor associated with very high blood ammonia (NH3) concentrations. Both twins showed a similar marked increase of venous NH3 concentrations after the administration of a single loading dose of VPA (800 mg).

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Year:  1985        PMID： 3928828     DOI： 10.1007/bf00313894

Source DB:  PubMed          Journal:  J Neurol        ISSN： 0340-5354            Impact factor:   4.849


  9 in total

1.  Secondary hyperammonaemia: a possible mechanism for valproate encephalopathy.

Authors:  D L Coulter; R J Allen
Journal:  Lancet       Date:  1980-06-14       Impact factor: 79.321

2.  Hyperammonemia with valproic acid therapy.

Authors:  D L Coulter; R J Allen
Journal:  J Pediatr       Date:  1981-08       Impact factor: 4.406

3.  A new method for screening for hyperammonemia.

Authors:  K Tada; K Okuda; K Watanabe; Y Iimura; S Yamada
Journal:  Eur J Pediatr       Date:  1979-02-08       Impact factor: 3.183

4.  Hyperammonemia and valproate-induced alterations of the state of consciousness. A report of 8 cases.

Authors:  G Zaccara; M Paganini; R Campostrini; G Arnetoli; R Zappoli; F Moroni
Journal:  Eur Neurol       Date:  1984       Impact factor: 1.710

5.  Acute changes of blood ammonia may predict short-term adverse effects of valproic acid.

Authors:  G Zaccara; R Campostrini; M Paganini; F Moroni; T Valenza; G Targioni; G Arnetoli; R Zappoli; A Baruzzi
Journal:  Neurology       Date:  1984-11       Impact factor: 9.910

6.  Sodium valproate associated with phenobarbital: effects on ammonia metabolism in humans.

Authors:  J M Warter; C Marescaux; C Brandt; L Rumbach; G Micheletti; G Chabrier; M Imler; D Kurtz
Journal:  Epilepsia       Date:  1983-10       Impact factor: 5.864

7.  Asymptomatic hyperammonemia in patients receiving valproic acid.

Authors:  J V Murphy; K Marquardt
Journal:  Arch Neurol       Date:  1982-09

8.  Effect of associated antiepileptic treatment on valproate-induced hyperammonemia.

Authors:  G Zaccara; M Paganini; R Campostrini; F Moroni; T Valenza; A Messori; M Bartelli; G Arnetoli; R Zappoli
Journal:  Ther Drug Monit       Date:  1985       Impact factor: 3.681

9.  [Sodium valproate: a hyperammonemic drug. Study in the epileptic and healthy volunteer].

Authors:  C Marescaux; J M Warter; M Laroye; L Rumbach; G Micheletti; C Koehl; M Imler; D Kurtz
Journal:  J Neurol Sci       Date:  1983-02       Impact factor: 3.181
  9 in total
  4 in total

Review 1.  Biochemical relationships between Reye's and Reye's-like metabolic and toxicological syndromes.

Authors:  J Osterloh; W Cunningham; A Dixon; D Combest
Journal:  Med Toxicol Adverse Drug Exp       Date:  1989 Jul-Aug

Review 2.  Valproate-induced hyperammonaemia superimposed upon severe neuropsychiatric lupus: a case report and review of the literature.

Authors:  Estee Chan; Fiona McQueen
Journal:  Clin Rheumatol       Date:  2012-12-28       Impact factor: 2.980

3.  State of stupor from valproic acid during chronic treatment: case report.

Authors:  S Gentile; C Buffa; C Ravetti; I Sacerdote
Journal:  Ital J Neurol Sci       Date:  1991-04

Review 4.  Clinical pharmacokinetics of valproic acid--1988.

Authors:  G Zaccara; A Messori; F Moroni
Journal:  Clin Pharmacokinet       Date:  1988-12       Impact factor: 6.447
  4 in total

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