Literature DB >> 3928362

Medical surveillance of exposed persons after exposure to PCBs, chlorinated dibenzodioxins and dibenzofurans after PCB transformer or capacitor incidents.

A Schecter.   

Abstract

The panel discussion from the perspective of occupational medicine regarding appropriate medical surveillance after a PCB transformer or capacitor incident is reviewed. A thorough occupational medicine history and physical examination is stressed for any worker or other patient who may have been exposed. Appropriate laboratory tests, including complete blood count with differential, serum chemistries, serial blood PCB determinations, fat biopsy to estimate furan and dioxin levels, if indicated, pulmonary function tests, chest X-rays, urinalysis including porphyrin measurement, nerve conduction velocity testing and other tests are discussed. No consensus was reached on recommended length of medical followup. Because the field is rapidly changing, yearly updates of medical protocols are warranted. In addition, the need for surveillance to be conducted by specialists with training and experience in the fields of occupational medicine and nursing was emphasized. It was stressed that measuring the chemicals and their levels in soot and air and then comparing these with the patient's blood or fat levels, in the case of PCBs, furans and dioxins, is vital. It was noted that at present no modality of treatment is known to be clinically efficacious in removing PCBs, furans and dioxins from tissues or blood.

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Year:  1985        PMID: 3928362      PMCID: PMC1568580          DOI: 10.1289/ehp.8560333

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN: 0091-6765            Impact factor:   9.031


  18 in total

1.  Decrease in vital capacity in PCB-exposed workers in a capacitor manufacturing facility.

Authors:  R Warshaw; A Fischbein; J Thornton; A Miller; I J Selikoff
Journal:  Ann N Y Acad Sci       Date:  1979-05-31       Impact factor: 5.691

2.  Transfer of polychlorinated biphenyls to the foetuses and offspring of mice.

Authors:  Y Masuda; R Kagawa; S Tokudome; M Kuratsune
Journal:  Food Cosmet Toxicol       Date:  1978-02

3.  Chloracne following environmental contamination by TCDD in Seveso, Italy.

Authors:  F Caramaschi; G del Corno; C Favaretti; S E Giambelluca; E Montesarchio; G M Fara
Journal:  Int J Epidemiol       Date:  1981-06       Impact factor: 7.196

4.  Levels of polychlorinated biphenyls (PCBs) and organochlorine pesticides in human milk and blood collected in Osaka Prefecture from 1972 to 1977.

Authors:  T Yakushiji; I Watanabe; K Kuwabara; S Yoshida; K Koyama; N Kunita
Journal:  Int Arch Occup Environ Health       Date:  1979-03-07       Impact factor: 3.015

5.  Alterations in drug metabolism in workers exposed to polychlorinated biphenyls.

Authors:  A P Alvares; A Fischbein; K E Anderson; A Kappas
Journal:  Clin Pharmacol Ther       Date:  1977-08       Impact factor: 6.875

6.  Liver structure and function in patients poisoned with chlordecone (Kepone).

Authors:  P S Guzelian; G Vranian; J J Boylan; W J Cohn; R V Blanke
Journal:  Gastroenterology       Date:  1980-02       Impact factor: 22.682

7.  Polychlorinated biphenyls (PCBs) inducible monooxygenases in rabbits and mice: species and organ specificities.

Authors:  A P Alvares; T H Ueng; J L Eiseman
Journal:  Life Sci       Date:  1982-03-01       Impact factor: 5.037

8.  Polychlorinated biphenyl contamination of nursing mothers' milk in Michigan.

Authors:  T M Wickizer; L B Brilliant; R Copeland; R Tilden
Journal:  Am J Public Health       Date:  1981-02       Impact factor: 9.308

9.  Monitoring breast milk contamination to detect hazards from waste disposal.

Authors:  W Rogan; B Gladen
Journal:  Environ Health Perspect       Date:  1983-02       Impact factor: 9.031

10.  Research needs for hepatic injury due to environmental agents.

Authors:  P S Guzelian
Journal:  Environ Health Perspect       Date:  1983-02       Impact factor: 9.031

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