Literature DB >> 3927838

Alteration of ribosomes and RNA polymerase in drug-resistant clinical isolates of Mycobacterium tuberculosis.

T Yamada, A Nagata, Y Ono, Y Suzuki, T Yamanouchi.   

Abstract

The biochemical mechanism of resistance to kanamycin, viomycin, and rifampin in five clinical isolates of Mycobacterium tuberculosis was studied. Resistance to viomycin and kanamycin was attributed to altered ribosomes, whereas resistance to rifampin was attributed to an alteration of RNA polymerase. Ribosomal resistance was, however, not the only way of expressing resistance to viomycin and kanamycin.

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Year:  1985        PMID： 3927838      PMCID： PMC180187          DOI： 10.1128/AAC.27.6.921

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  16 in total

1.  Resistance to viomycin conferred by RNA of either ribosomal subunit.

Authors:  T Yamada; Y Mizugichi; K H Nierhaus; H G Wittmann
Journal:  Nature       Date:  1978-10-05       Impact factor: 49.962

2.  Altered ribosomes in antibiotic-resistant mutants of Mycobacterium smegmatis.

Authors:  T Yamada; K Masuda; Y Mizuguchi; K Suga
Journal:  Antimicrob Agents Chemother       Date:  1976-05       Impact factor: 5.191

3.  Mode of action of rifampin on mycobacteria. II. Biosynthetic studies on the inhibition of ribonucleic acid polymerase of Mycobacterium bovis BCG by rifampin and uptake of rifampin- 14 C by Mycobacterium phlei.

Authors:  K Konno; K Oizumi; S Oka
Journal:  Am Rev Respir Dis       Date:  1973-06

4.  Inhibition of polyphenylalanine synthesis on ribosomes of mycobacteria by tuberactinomycin-N.

Authors:  T Yamada; K Kawaguchi; K Masuda; K Shoji; M Hori
Journal:  Am Rev Respir Dis       Date:  1972-11

5.  Supercoiled circular DNA-protein complex in Escherichia coli: purification and induced conversion to an opern circular DNA form.

Authors:  D B Clewell; D R Helinski
Journal:  Proc Natl Acad Sci U S A       Date:  1969-04       Impact factor: 11.205

6.  Biochemical mechanism of kanamycin resistance in Mycobacterium tuberculosis.

Authors:  S Mitsuhashi; T Tanaka; H Kawabe; H Umezawa
Journal:  Microbiol Immunol       Date:  1977       Impact factor: 1.955

7.  Genetic and biochemical studies on drug-resistant mutants in Mycobacterium smegmatis.

Authors:  Y Mizuguchi; K Suga; K Masuda; T Yamada
Journal:  Jpn J Microbiol       Date:  1974-11

8.  Pleiotropic antibiotic resistance mutations associated with ribosomes and ribosomal subunits in Mycobacterium smegmatis.

Authors:  T Yamada; K Masuda; K Shoji; M Hori
Journal:  Antimicrob Agents Chemother       Date:  1974-07       Impact factor: 5.191

9.  Mechanism of action of rifampin on Mycobacterium smegmatis.

Authors:  R J White; G C Lancini; L G Silvestri
Journal:  J Bacteriol       Date:  1971-11       Impact factor: 3.490

10.  Protein synthesis in Mycobacterium tuberculosis H37Rv and the effect of streptomycin in streptomycin-susceptible and -resistant strains.

Authors:  M S Shaila; K P Gopinathan; T Ramakrishnan
Journal:  Antimicrob Agents Chemother       Date:  1973-09       Impact factor: 5.191
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  8 in total

Review 1.  Comparative pharmacokinetics and pharmacodynamics of the rifamycin antibacterials.

Authors:  W J Burman; K Gallicano; C Peloquin
Journal:  Clin Pharmacokinet       Date:  2001       Impact factor: 6.447

2.  Relationship between rifampin MICs for and rpoB mutations of Mycobacterium tuberculosis strains isolated in Japan.

Authors:  H Ohno; H Koga; S Kohno; T Tashiro; K Hara
Journal:  Antimicrob Agents Chemother       Date:  1996-04       Impact factor: 5.191

3.  Structure of 5S rRNA in actinomycetes and relatives and evolution of eubacteria.

Authors:  E Dams; T Yamada; R De Baere; E Huysmans; A Vandenberghe; R De Wachter
Journal:  J Mol Evol       Date:  1987       Impact factor: 2.395

4.  Inactivation of rifampin by Nocardia brasiliensis.

Authors:  K Yazawa; Y Mikami; A Maeda; M Akao; N Morisaki; S Iwasaki
Journal:  Antimicrob Agents Chemother       Date:  1993-06       Impact factor: 5.191

5.  Mutation of tlyA confers capreomycin resistance in Mycobacterium tuberculosis.

Authors:  Courtney E Maus; Bonnie B Plikaytis; Thomas M Shinnick
Journal:  Antimicrob Agents Chemother       Date:  2005-02       Impact factor: 5.191

6.  A new approach for the discovery of antibiotics by targeting non-multiplying bacteria: a novel topical antibiotic for staphylococcal infections.

Authors:  Yanmin Hu; Alireza Shamaei-Tousi; Yingjun Liu; Anthony Coates
Journal:  PLoS One       Date:  2010-07-27       Impact factor: 3.240

7.  Identification of the biosynthetic gene cluster and an additional gene for resistance to the antituberculosis drug capreomycin.

Authors:  Elizabeth A Felnagle; Michelle R Rondon; Andrew D Berti; Heidi A Crosby; Michael G Thomas
Journal:  Appl Environ Microbiol       Date:  2007-05-11       Impact factor: 4.792

Review 8.  Microbial Resistance Movements: An Overview of Global Public Health Threats Posed by Antimicrobial Resistance, and How Best to Counter.

Authors:  Sameer Dhingra; Nor Azlina A Rahman; Ed Peile; Motiur Rahman; Massimo Sartelli; Mohamed Azmi Hassali; Tariqul Islam; Salequl Islam; Mainul Haque
Journal:  Front Public Health       Date:  2020-11-04
  8 in total

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