[Role of emotions in cholinergic mechanisms of formation and reproduction of a bilateral conditioned avoidance reflex].

In experiments on rats it was shown that during elaboration of a bilateral avoidance conditioned reflex against scopolamine background, facilitation of the learning process takes place only at simultaneous elimination of the emotional fear reaction expressed in a decrease of the heart-rate. The presence of non-cholinergic mechanisms participating in generation of high-frequency (8-12 c/s) hippocampal regular activity is necessary for the reproduction of instrumental avoidance reaction against the scopolamine background. A resistivity of emotional fear reaction to cholinoblocators in animals learning with difficulty, is revealed (monitored according to conditioned decreasing of the heart-rates). This fact points to the non-cholinergic nature of a definite type of emotional passive fear reaction. The theory of memory dissociation explains the inversely-proportional dependence of the reflex stability after cancelling of scopolamine administration upon the duration of reaction stabilization against the background of the drug.