Literature DB >> 3926575

Activated oncogenes in a rat hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline.

F Ishikawa, F Takaku, M Nagao, M Ochiai, K Hayashi, S Takayama, T Sugimura.   

Abstract

The presence of activated oncogenes in several rat hepatocellular carcinomas induced by 2-amino-3-methylimidazo[4,5-f]-quinoline (IQ) was examined by NIH 3T3 cell transfection assay and Southern blot analysis. In one tumor, IQ4, rat H-ras-1 and another oncogene that did not belong to the ras family were found to be activated.

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Year:  1985        PMID： 3926575

Source DB:  PubMed          Journal:  Jpn J Cancer Res        ISSN： 0910-5050


  9 in total

1.  Effects of endotoxin on expression of ras, p53 and bcl-2 oncoprotein in hepatocarcinogenesis induced by thioacetamide in rats.

Authors:  J M Yang; D W Han; Q C Liang; J L Zhao; S Y Hao; X H Ma; Y C Zhao
Journal:  World J Gastroenterol       Date:  1997-12-15       Impact factor: 5.742

2.  Tumorigenicity of simian virus 40-hepatocyte cell lines: effect of in vitro and in vivo passage on expression of liver-specific genes and oncogenes.

Authors:  C D Woodworth; J W Kreider; L Mengel; T Miller; Y L Meng; H C Isom
Journal:  Mol Cell Biol       Date:  1988-10       Impact factor: 4.272

Review 3.  Human cancer and cellular oncogenes.

Authors:  S Nishimura; T Sekiya
Journal:  Biochem J       Date:  1987-04-15       Impact factor: 3.857

4.  Activation of rat c-raf during transfection of hepatocellular carcinoma DNA.

Authors:  F Ishikawa; F Takaku; K Hayashi; M Nagao; T Sugimura
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

5.  Molecular cloning of an oncogene from a human hepatocellular carcinoma.

Authors:  T Ochiya; A Fujiyama; S Fukushige; I Hatada; K Matsubara
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

6.  Characterization of liver epithelial cells transfected with myc and/or ras oncogenes.

Authors:  S C Strom; J B Faust; E Cappelluti; R B Harris; N D Lalwani
Journal:  Dig Dis Sci       Date:  1991-05       Impact factor: 3.199

7.  Rapid detection of xenotransplanted human tissues using in situ hybridization.

Authors:  T Obara; C J Conti; M Baba; J H Resau; A L Trifillis; B F Trump; A J Klein-Szanto
Journal:  Am J Pathol       Date:  1986-03       Impact factor: 4.307

8.  Absence of H-ras point mutation at codon 12 in N-methyl-N-nitrosourea-induced hepatocellular neoplasms in the rat.

Authors:  H Li; G H Lee; L X Cui; J Liu; K Nomura; K Ohtake; T Kitagawa
Journal:  J Cancer Res Clin Oncol       Date:  1990       Impact factor: 4.553

Review 9.  Past, present, and future of mutagens in cooked foods.

Authors:  T Sugimura
Journal:  Environ Health Perspect       Date:  1986-08       Impact factor: 9.031
  9 in total

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