Literature DB >> 3926363

Non-steroidal anti-inflammatory drugs in combination. Experimental observations.

D G Palmer, J Highton, M J Mackinnon, D B Myers.   

Abstract

Diflunisal in combinations with oxaprozin, indomethacin and sodium meclofenamate produced significant synergistic suppression of carrageenan-induced oedema of the rat foot-pad. Oxaprozin, benoxaprofen, indomethacin, diflunisal, sodium meclofenamate and auranofin in some paired combinations but not in others were associated with a greater effect than the component drugs used alone. Antagonism was demonstrated with other combinations of these drugs.

Entities:  

Mesh:

Substances:

Year:  1985        PMID: 3926363

Source DB:  PubMed          Journal:  Clin Exp Rheumatol        ISSN: 0392-856X            Impact factor:   4.473


  3 in total

1.  Predictability of the clinical potency of NSAIDs from the preclinical pharmacodynamics in rats.

Authors:  A Mukherjee; V G Hale; O Borga; R Stein
Journal:  Inflamm Res       Date:  1996-11       Impact factor: 4.575

Review 2.  Oxaprozin. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.

Authors:  P A Todd; R N Brogden
Journal:  Drugs       Date:  1986-10       Impact factor: 9.546

3.  Interaction studies of tilomisole, aspirin, and naproxen in acute and chronic inflammation with assessment of gastrointestinal irritancy in the rat.

Authors:  W Calhoun; S C Gilman; L J Datko; T W Copenhaver; R P Carlson
Journal:  Agents Actions       Date:  1992-05
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.